None listed
Conditions
Brief summary
Ankylosing spondylitis (AS) is a chronic and systemic rheumatic disease that causes inflammation and ankylosis of the axial skeleton. Disease progression often leads to spinal pain, stiffness, strain, deformity, functional impairment, disability and poor quality of life. From a biological point of view, physical exercise is indicated as a treatment for any chronic pathology and is proposed as a successful complement to the pharmacological treatment of any disease. The gut microbiota can contribute to the metabolic health of the human host and, when abnormal, affects the phenotype of immune cells, increasing the risk of autoimmunity. On the other hand, exercise is a potential modulator of gut microbiome composition and is associated with increased biodiversity and representation of taxa with beneficial metabolic functions. Therefore, we hypothesized that a lifestyle change could improve disease progression (spinal mobility, stiffness, tension, deformity, functional impairment, disability, and poor quality of life).
Interventions
Excercise group:
Tabata method that consists of batches of one or more different exercises (high knees, squats, basic burpees, plank or climbers) performed during 8-20 intervals with 10 second interpersed breaks. The excercise will led at home supervised by a physiotherapist. We will achieve two 4-minute sessions per week high intensity workout, the level of intensity was not assessed . The intervention will last 3 months and there were session attendance checklists supervised by a physiotherap
Excercise group: Tabata method that consists of batches of one or more different exercises (high knees, squats, basic burpees, plank or climbers) performed during 8-20 intervals with 10 second interpersed breaks. The excercise will led at home supervised by a physiotherapist. We will achieve two 4-minute sessions per week high intensity workout, the level of intensity was not assessed . The intervention will last 3 months and there were session attendance checklists supervised by a physiotherapist.
Sponsors
Universidad Camilo José Cela
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients diagnosed with Ankylosing Spondylitis according to the modified criteria of New York
Exclusion criteria
Any systemic disorder that contraindicates exercise, active peripheral arthritis, total spinal ankylosis, or C-reactive protein (PCR) more than 10 times the normal value. Patients will also be excluded if their treatment has been modified 2 months before the start of the study.
Outcome results
None listed