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Effects of a blackcurrant powder blend on repeated high-intensity cycling performance, attention and lung function under pollution exposure in highly trained male cyclists.

Effects of a blackcurrant Nootropic powder on repeated high-intensity cycling performance, cognition and respiratory function under ozone exposure in highly trained male cyclists.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12622001198718
Enrollment
10
Registered
2022-09-07
Start date
2022-01-24
Completion date
2022-06-20
Last updated
2022-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Exposure to ground-level ozone impairs lung function and induces systemic inflammation. Outdoor exercise is advocated for both its physical and mental health benefits, yet exercising in air pollution induces an array of pathophysiological responses and shown to be related to cognitive decline. Blackcurrants contain high levels of polyphenols that may mitigate the damaging effects of ozone on lung inflammation, and positively influence mood and cognition. The exercising athlete is more susceptible to the influence of air pollution due to increased ventilation, and breathing velocity transporting pollutants further into the respiratory tract. The objective of this study is to see if 7 day supplementation of blackcurrant powder reduces respiratory symptoms and lung inflammation, and assists exercise performance.

Interventions

Blackcurrant powder supplementation and ozone exposure. Healthy participants will supplement with a proprietary blackcurrant powder (Arepa) before undergoing an exercise trial under conditions of ozone exposure. Participants will consume either blackcurrant (BC) or placebo (PL) for seven days prior to completing a cycling protocol on a cycle ergometer in a chamber with ozone set to 0.25 ppm. Treatments (BC or PL) will be administered in purple, berry flavoured gelatine capsules at a dose of 4.3

Blackcurrant powder supplementation and ozone exposure. Healthy participants will supplement with a proprietary blackcurrant powder (Arepa) before undergoing an exercise trial under conditions of ozone exposure. Participants will consume either blackcurrant (BC) or placebo (PL) for seven days prior to completing a cycling protocol on a cycle ergometer in a chamber with ozone set to 0.25 ppm. Treatments (BC or PL) will be administered in purple, berry flavoured gelatine capsules at a dose of 4.3 mg/kg body weight. Subjects will take their prescribed dose daily orally for a period of 7 days before reporting to the lab for testing. Participants will be oversupplied with capsules and a countback will be used to determine adherence to the supplement protocol. Participants will complete a preload protocol of 10 min @ 50%, 10 min @ 60% and 5 min @ 70% peak power output (PPO) followed by a 10 min rest. They will then complete a 4 km time trial (TT) as fast as possible. The PPO for the preload will be obtained from a VO2 max test conducted at the first visit and familiarisation trial. There is a 2-week washout before the next supplementation period. All exercise sessions (with the exception of the VO2 and familiaristaion) will be performed under ozone (0.25 ppm) conditions. Participants will be monitored at all times throught the entire study progress. Cycling data (power, distance, cadence, time) will be automatically recorded by the ergometers associated software). Metabolic data will be collected using breath-by-breath analysis using a metabolic cart.

Sponsors

High Value Nutrition
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Caregiver)

Eligibility

Sex/Gender
Male
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

Highly-trained male cyclists with a training history of > 2 years, no chronic health conditions or respiratory conditions (i.e. asthma or exercise-induced asthma or breathlessness), no acute respiratory illness within the last month, no medications that affect respiratory, cardiovascular or immune function, and be restricted to males over 18 years of age.

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026