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Influence of health care information on reproductive decisions

Women’s interest, knowledge, and attitudes relating to anti-Mullerian hormone testing: A randomised controlled trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12622001136796
Enrollment
967
Registered
2022-08-17
Start date
2022-11-21
Completion date
2022-12-19
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The Anti-Mullerian hormone (AMH) test is currently being promoted misleadingly by online companies and fertility clinics as a fertility test for women. Importantly, research has demonstrated the test is not predictive of current or future fertility potential. It is vital women receive evidence-based information about this test free from commercial interests in order make informed decisions regarding their reproductive planning. This study aims to co-design an evidence-based information guide with key stakeholders (clinicians and consumers) and evaluate it with two samples of women, living either in Australia or The Netherlands. The information guide will be tested using an online randomised experimental design to assess the impact of the information on women’s intention to have the test, knowledge about AMH, attitudes towards the blood test and psychosocial outcomes. Hypothesis: It is hypothesised that women who receive the intervention (evidence-based info) will have lower interest and intention in getting an AMH test, and have higher knowledge, than women who receive the control information (misleading information currently online). Potential significance of the current study: Given the plethora of misleading information about the AMH test online, this study will produce crucial, evidence-based information for consumers, with the goal of improving informed decision-making and reducing inappropriate test usage.

Interventions

The aim of this trial is to test and evaluate the impact of co-designed, evidence-based information about the anti-mullerian hormone (AMH) test on women's attitudes, interest in the test, psychosocial outcomes and reproductive decision-making. The intervention materials (evidence-based information about the AMH test) have been co-designed with a number of clinicians (IVF specialists, GPs, gynaecologists) and women (whom are the target audience of AMH test marketing). Participants will be ran

The aim of this trial is to test and evaluate the impact of co-designed, evidence-based information about the anti-mullerian hormone (AMH) test on women's attitudes, interest in the test, psychosocial outcomes and reproductive decision-making. The intervention materials (evidence-based information about the AMH test) have been co-designed with a number of clinicians (IVF specialists, GPs, gynaecologists) and women (whom are the target audience of AMH test marketing). Participants will be randomised to 1 of 2 conditions; the intervention or the control arm. The intervention arm will present women with co-designed, evidence-based information about the AMH blood test. Participants will be randomised to either the intervention or control using Qualtrics survey software. After viewing the information presented in an online, written format (soft-copy written materials with matching images), participants will complete several outcome measures. It is anticipated it will take approximately 5-10 minutes to view the intervention materials, plus a further 5-10 minutes to complete the outcome measures. Detailed description of intervention materials: A co-designed, evidence-based information guide on the AMH blood test, concerning the nature of the test and its poor predictive value when it comes to predicting current or future fertility, as well as premature ovarian failure or age of menopause. It will also elaborate, with evidence-based information, on the following subjects: Who might benefit from an AMH-test; Risks and downsides of taking the test; costs of the test (appropriated to the country for which the guide is made); And information on preconception health and where to seek more information.

Sponsors

The University of Sydney
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Caregiver)

Eligibility

Sex/Gender
All
Age
25 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

Nulliparous females aged 25-40 years with an active or future childbearing wish, living in Australia or The Netherlands, who have not previously had an AMH test.

Exclusion criteria

*Not assigned female at birth *No current or future childbearing wish *Have previously given birth *Currently pregnant *Have previously had an AMH blood test

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 5, 2026