None listed
Conditions
Brief summary
The research study aims to explore the potential interaction between application time of the day and short-term myopia (or ‘short-sightedness’) control contact lens wear and different lighting conditions. Participants will wear contact lenses and goggles fitted with one of the three different light filters (neutral density filters, blue filters and red filters) during each visit and their eyes will be measured using non-invasive methods at the beginning and the end of each visit.
Interventions
There will be six one-hour visits in total, where three visits scheduled in the morning and three in the afternoon on different days. During each visit, participants will be wearing commercially available multi-focal contact lenses individualized based on their presenting prescription, simultaneously with goggles (commercial welding goggles) fitted with one type of the light filters (in random order): neutral density filters, red filters and blue filters. Same contact lenses will be provided acr
There will be six one-hour visits in total, where three visits scheduled in the morning and three in the afternoon on different days. During each visit, participants will be wearing commercially available multi-focal contact lenses individualized based on their presenting prescription, simultaneously with goggles (commercial welding goggles) fitted with one type of the light filters (in random order): neutral density filters, red filters and blue filters. Same contact lenses will be provided across all visits. Audiobooks will be played at the background for participants' entertainment while they are sitting still in a chair during this one hour period. Participants will attend the two control visits (with neutral density filters, morning and afternoon) first, followed by the other four visits (with blue or red filters) in a random order. Wash out period between the four visits will be at least 24 hours (no wash out for the neutral density filters conditions as they are considered as placebo). The researcher will be monitoring participant's adherence to the intervention via verbal confirmation during and at the end of study.
Sponsors
Brien Holden Vision Institute Limited
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
1. Adults with good general health, age range 18 to 35 years 2. Best-corrected visual acuity of 20/20 or better in each eye, short-sighted (myopic spherical equivalent between 0.5D and 5D) 3. Experienced contact lens wearers 4. Have ocular health findings considered to be ‘normal’ (E.g. no ocular diseases, colour vision deficiency or history of eye surgery) 5. Willing to sign informed consent and comply with study schedule
Exclusion criteria
1. Systemic diseases that may affect ocular health (e.g. hypertension, diabetes mellitus, etc.) 2. Ocular disease or history of eye surgery 3. Use of myopia control medications or devices 4. Use of melatonin or any pharmacological sleep aids 5. Use of or a need for any medications which may alter normal ocular findings / are known to affect a participant’s ocular health / physiology either in an adverse or beneficial manner 6. Travelled between different time zones within two months upon participating in the study 7. Current smoker
Outcome results
None listed