None listed
Conditions
Brief summary
The aim of the study is to define the principles of caffeine supplementation in sports based on heart rate variability (HRV) analysis. The study aims to capture the individually variable characteristics that influence the level of objective response of the body to different doses of caffeine. Participants will be randomly divided into 3 groups (placebo, 3 mg/kg, and 6 mg/kg body weight). We hypothesize that explaining the relationship between muscle response and HRV to caffeine doses will allow detailed recommendations to athletes.
Interventions
In the study, caffeine consumption is investigated at a dosage of 3 (group A) and 6 mg/kg body weight (group B).
Caffeine will be administered orally in a single dose, based on body weight, in clear cellulose capsules (hydroxypropylmethylcellulose 100%).
Participants will be instructed to avoid foods containing caffeine for 24 hours prior to testing. All measurements will be taken between 8:00 am and 3:00 pm.
The caffeine dose will be randomly selected.
All measurements will be performed in univ
In the study, caffeine consumption is investigated at a dosage of 3 (group A) and 6 mg/kg body weight (group B). Caffeine will be administered orally in a single dose, based on body weight, in clear cellulose capsules (hydroxypropylmethylcellulose 100%). Participants will be instructed to avoid foods containing caffeine for 24 hours prior to testing. All measurements will be taken between 8:00 am and 3:00 pm. The caffeine dose will be randomly selected. All measurements will be performed in university laboratories. After ingestion of caffeine, participants will be continuously supervised until the end of the measurement and for the following 24 hours.
Sponsors
Poznan University of Medical Sciences
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy athletes and healthy volunteers
Exclusion criteria
• lack of informed consent to participate in research, • hypersensitivity to caffeine due to the polymorphism of the CYP1A2 gene • diseases of the cardiovascular system, • chronic disease impairing the functioning of the musculoskeletal system, • diabetes, • epilepsy, • pregnancy, • infections, • inflammatory diseases, • stroke history, • oncological diseases, • electronic life support systems (pacemakers, active prostheses, etc.) • use of preparations that interact with caffeine, i.e. ephedrine, theophylline, and echinacea • hypertension (over 140/90 mmHg)
Outcome results
None listed