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Frailty predicts mortality in patients with upper gastrointestinal bleed: A single centre observational study.

Frailty predicts mortality in patients with Upper Gastrointestinal bleed: A prospective cohort study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12622000821796
Enrollment
229
Registered
2022-06-10
Start date
2015-10-09
Completion date
2017-06-29
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this observational study is to check whether frailty predicts mortality/death in patients who are in the hospital for an upper gastrointestinal bleeding (UGIB) episode. We hypothesize that frailty is an independent predictor of death in patients with UGIB and other important hospital outcomes.

Interventions

Assessing the role of frailty as measured by the Canadian Study of Health and Ageing (CSHA) clinical frailty scale, age, and other risk scores (Charles comorbidity index, Glasgow Blatchford score, AIMS 65 score) in predicting mortality in consecutive patients with upper gastrointestinal bleed over 21 months. The score of frailty is assigned by an investigator at the time of upper GI bleed from an overall clinical assessment after their informed consent. The rest of the data is collected from the

Assessing the role of frailty as measured by the Canadian Study of Health and Ageing (CSHA) clinical frailty scale, age, and other risk scores (Charles comorbidity index, Glasgow Blatchford score, AIMS 65 score) in predicting mortality in consecutive patients with upper gastrointestinal bleed over 21 months. The score of frailty is assigned by an investigator at the time of upper GI bleed from an overall clinical assessment after their informed consent. The rest of the data is collected from the medical records. The 30-day follow-up data is either obtained from the medical records if available or via telephone follow-up.

Sponsors

Liverpool Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

Age > or = 18 years Informed consent Symptoms of Upper gastrointestinal bleed (malaena, haematemesis, coffee-ground emesis, Haematochezia)

Exclusion criteria

<18 years and >100 years no informed consent Lower Gastrointestinal bleed on endoscopic assessment Bleeding without any source on endoscopic assessment No bleeding on endoscopic assessment

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 9, 2026