None listed
Conditions
Brief summary
Laser peripheral iridotomy is used to treat narrow and closed-angle glaucoma and eyes with narrow anterior chamber angle to prevent progression to glaucoma. The laser peripheral iritodomy can be done in any location in the peripheral iris, however traditionally, it has been performed in the superior 12 o’clock position. The superior and temporal (3 o’clock for left eye, 9 o’clock for right eye) sites are the most common sites for laser peripheral iridotomy. Rarely, some patients may experience visual disturbances after laser peripheral iridotomy. These are known as dysphotopsia symptoms and typically described as grey or blue horizontal or slightly curved line. The purpose of this study is to assess the whether superior or temporal placement the iridotomy hole is associated with incidence of dysphotopsia symptoms. The hypothesis is that superiorly placed laser peripheral iridotomies are associated with reduced incidence of dysphotopsia symptoms.
Interventions
Neodymium-doped yttrium aluminium garnet (Nd:YAG) laser (Ellex Tango) will be used to perform the laser peripheral iridotomy procedure. One eye for each participant will undergo superior placement of the iridotomy hole and the other eye assigned temporal/nasal placement of the iridotomy hole. The procedure will be done at a private Sydney ophthalmology clinic by an experienced ophthalmologist. The procedure usually takes 5-10 minutes after which participants may return home. Participants include
Neodymium-doped yttrium aluminium garnet (Nd:YAG) laser (Ellex Tango) will be used to perform the laser peripheral iridotomy procedure. One eye for each participant will undergo superior placement of the iridotomy hole and the other eye assigned temporal/nasal placement of the iridotomy hole. The procedure will be done at a private Sydney ophthalmology clinic by an experienced ophthalmologist. The procedure usually takes 5-10 minutes after which participants may return home. Participants included in the study will have one eye undergo superiorly placed laser peripheral iridotomy and the other assigned to temporal location by default. The procedure will be performed sequentially with the superior laser peripheral iridotomy (LPI) performed first. The selected eye will be based on presenting symptoms - in the eye with poorer visual acuity, clinically narrower angles and/or smaller anterior chamber depth. Within one week, the participant will undergo the second LPI performed temporally/nasally. Adherence to the intervention will be monitored using clinical notes.
Sponsors
Rachel Xuan
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1) Participants (>18 years old) diagnosed with primary angle closure glaucoma or primary angle-closure suspect in both eyes and requiring laser peripheral iridotomy intervention 2) Participants are able to attend required study visits
Exclusion criteria
1) Participants who have undergone previous laser peripheral iridotomy procedure in either eye 2) Participants who have undergone previous intraocular surgery 3) Participants with asymmetrical ptosis of more than 2mm 4) Participants with any active intraocular inflammation at the time of undergoing laser peripheral iridotomy procedure 5) Participants with a history of acute-attack angle closure glaucoma
Outcome results
None listed