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Optimising heat therapy for treating high blood pressure

The effect of acute passive heat therapy on 24-h ambulatory blood pressure in patients with hypertension

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12622000720718
Enrollment
16
Registered
2022-05-19
Start date
2022-09-05
Completion date
2022-12-02
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to examine the effect of heat therapy on taha tinana (physical health; specifically, 24-h blood pressure) in patients with hypertension. Secondary outcomes will assess the effect on taha wairua (spiritual wellbeing), taha whanau (family health) and taha hinengaro (mental health). A randomised cross-over study will recruit 10 participants who are currently taking at least one anti-hypertensive medication. They will complete 4 sessions: 1) 20-min hot water immersion (40°C), 2) 40-min hot water immersion (40°C), 3) 40-min thermoneutral water immersion (~36°C, to establish the role of the water temperature specifically), and 4) control (no exposure). Physiological measures will be taken during exposure to characterise the stimulus. Following each exposure participants will be fitted with an ambulatory blood pressure monitor (and accelerometer to standardise activity levels) for the following 24 h to quantify the magnitude and duration of post-session hypotension.

Interventions

All participants will complete 3 water immersion sessions and a control session (in a randomised order): 1) 20-min hot-water immersion (40°C), 2) 40-min hot-water immersion (40°C), 3) 40-min thermoneutral-water immersion (~36°C, to establish the role of the water temperature specifically). There will be a 7-day washout between exposures. 1. 20-min hot-water immersion (40°C) Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supe

All participants will complete 3 water immersion sessions and a control session (in a randomised order): 1) 20-min hot-water immersion (40°C), 2) 40-min hot-water immersion (40°C), 3) 40-min thermoneutral-water immersion (~36°C, to establish the role of the water temperature specifically). There will be a 7-day washout between exposures. 1. 20-min hot-water immersion (40°C) Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the PI or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete a single 20-min hot water immersion session in 40 °C water. Participants will be seated upright with water approximately nipple level. Duration: 20 min. 2. 40-min hot-water immersion (40°C) Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the PI or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete a single 40-min hot water immersion session in 40 °C water. Participants will be seated upright with water approximately nipple level. Duration: 40 min. 3. 40-min thermoneutral-water immersion (~36°C) Location: School of Physical Education, Sport and Exercise Sciences Aquatic Facility (University of Otago, Dunedin). Supervision: This session will be supervised by an American College of Sports Medicine (ACSM) registered clinical exercise physiologist (CEP), and the PI or a research assistant; all supervising researchers are first aid trained. Attendance and session particulars (e.g., physiological indices etc.) will be recorded at each session by the supervising researcher. Exposure: Participants will complete a single 40-min thermo-neutral water immersion session in ~36 °C water. Participants will be seated upright with water approximately nipple level. Duration: 40 min.

Sponsors

University of Otago
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
35 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

Participants will be screened as per criteria listed below: Inclusion criteria: - Aged > 35 y or older - Prescribed and regularly taking at least 1 anti-hypertensive medication - Patient gives written consent - Patient is able to travel to the study centre to complete all sessions.

Exclusion criteria

Exclusion criteria: - Aged < 35 y - Contraindication to maximal exercise testing (see Appendix) - Unstable angina - Recent myocardial infarction (< 3 months ago) - History of orthostatic intolerance/hypotension - Current pregnancy - New anti-hypertensive pharmaceutical initiated recently - Any other medical condition deemed a significant risk to study participation.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026