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Using muscle strength as a predictor for walking ability after stroke

Using muscle strength as a predictor for walking ability after stroke

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12622000711718
Enrollment
93
Registered
2022-05-17
Start date
2022-09-14
Completion date
2025-02-05
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In this study, we aim to determine the relationship between clinical measures of early muscle activity in the affected lower limb and future walking speed for stroke survivors who were initially unable to walk. Our hypothesis is that muscle strength recovery will be a significant predictor of future walking speed. The muscle group we will measure include muscles that extend the hip and knees as well as the muscles that move the ankle joints. We will measure muscle strength manually and using surface electromyography to 'listen' for any muscle activity present. We will measure walking speed once the participant is able to walk independently. These measurements will be taken at 1,2,3,4,8,12 and 26 weeks post stroke.

Interventions

After a stroke, reduced muscle strength is a main cause of reduced ability to walk. In this observational study, we'll examine the relationship between muscle strength and walking ability, and using muscle strength to predict walking speed at 6 months. Muscle strength will be measured using manual muscle test (MMT) and for muscles scoring at 0 or 1 on the MMT, a surface electromyography (EMG) reading will be recorded to ascertain the actual amount of muscle activity. We'll measure the muscl

After a stroke, reduced muscle strength is a main cause of reduced ability to walk. In this observational study, we'll examine the relationship between muscle strength and walking ability, and using muscle strength to predict walking speed at 6 months. Muscle strength will be measured using manual muscle test (MMT) and for muscles scoring at 0 or 1 on the MMT, a surface electromyography (EMG) reading will be recorded to ascertain the actual amount of muscle activity. We'll measure the muscle strength for all eligible stroke survivors who were initially non-ambulant post stroke onset. Walking speed will be measured when the stroke survivor is able to walk independently. The follow up period will be at 1, 2,3,4,8,12, 26 and 52 weeks following stroke onset. Muscle strength testing procedures: - 4 trials will be performed to ascertain muscle strength for hip and knee extensors, as well as ankle dorsiflexor and plantar flexors - the participants will lie in supine with their particle limb positioned at 90 degrees of hip and knee flexion on a stool as standardised positions for testing of muscle strength - if the participant scores 0 or 1 on manual muscle test, we will perform EMG for relevant muscle groups only - EMG electrodes will be positioned longitudinally over the innervation zone and distal tendon to ascertain muscle activity, and a third electrode as reference on a boney prominence - the actual reading from EMG machine will be recorded for all 4 attempts - the testing will be performed by either the site physiotherapist or the researcher - the approximate testing procedure will take 10-15minutes, and we will assess muscle strength at all timepoints in this study up to 26 weeks. At 52 weeks (12 months), we will follow up with phone call to participants who were not able to walk at 6 months to ascertain walking ability at 12 months.

Sponsors

Australian Catholic University
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Adult stroke survivors within 2 weeks of stroke Unable to walk independently (defined as Functional Ambulation Category (0-5) of less than or equal to 3) Able to give written or oral informed consent

Exclusion criteria

A history of clinical conditions affecting mobility A progressive neurological disease An inability to understand verbal or demonstrated instructions to perform outcome measures Medical contraindications to perform outcome measures Likely discharge destination outside of Sydney Metropolitan area

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026