None listed
Conditions
Brief summary
The aim of this study is to determine the effect of increased sugar consumption on the composition of breast milk and to assess variations in breast milk composition across the day. The intervention within this study includes two different diets; one control and one higher in sugar. A cross-over design will be used where control and higher sugar diets will be provided in a random order to each woman across two days. Women will be asked to manually express small amounts of breast milk each hour throughout the day (alongside consumption of the provided diets). Breast milk will be analysed for triglyceride, lactose, protein and fatty acid concentrations.
Interventions
The intervention diet will consist of a full days food consumption totalling to ~2500 calories and will include ~65g more sugar than the control diet. The foods provided consist of breakfast (cereal/toast/banana), lunch (pasta salad) and dinner (chicken stir-fry) plus two snacks (yogurt/fruit/crackers/cheese). The extra sugar will be incorporated in small changes such as adding sugar to cereal, honey on yogurt and a can of soda with lunch. The meals will be prepared and packed by the student in
The intervention diet will consist of a full days food consumption totalling to ~2500 calories and will include ~65g more sugar than the control diet. The foods provided consist of breakfast (cereal/toast/banana), lunch (pasta salad) and dinner (chicken stir-fry) plus two snacks (yogurt/fruit/crackers/cheese). The extra sugar will be incorporated in small changes such as adding sugar to cereal, honey on yogurt and a can of soda with lunch. The meals will be prepared and packed by the student investigator (SI) and delivered to participants homes ready for consumption. The intervention will span one day (12 hours) and will occur once, at least a week apart from the control. Adherence to the study diets will be monitored by weighing returned containers to estimate percentage consumption of meals and by using documentation designed to record extra details (e.g. consumed only half of dinner for X reason, consumed an orange at X time for X reason, consumed X amount of water at X time).
Sponsors
University of Adelaide
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
21 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
• Healthy mothers and singleton infants born at full term (>38 weeks gestation) • Mothers between the ages of 21-35 years • Mothers with a BMI between 20 and 30 kg/m2 • Infants between 6 and 20 weeks of age at the time of recruitment • Mother and infants have no self-reported underlying medical conditions/special dietary requirements which result in restriction of any major food groups (e.g. vegan/dairy allergy) • Mother able to give informed consent for themselves and their infants • Mothers have been exclusively breastfeeding (with the exception of additional water or medication such as paracetamol suspensions) their infant since birth
Exclusion criteria
• Infants who were born by caesarean section • Infants who are fed formula milk or fed a mixture of breast milk and formula • Mothers who are struggling with breast feeding and/or are unable to manually express milk. • Mother and/or baby who has an allergy/intolerance/aversion to the study diet (e.g. lactose intolerance).
Outcome results
None listed