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The impact of healthcare communication on medical decision-making

Online study investigating impact of anecdotal stories of In Vitro Fertilisation (IVF) success on medical decision-making in female volunteers

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12622000576729
Enrollment
645
Registered
2022-04-19
Start date
2022-05-10
Completion date
2022-05-30
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Prior research has found that couples continue after multiple unsuccessful cycles of IVF despite being aware of limited chances of success because they interpret their own chances of success in a positive light (Copp et al., 2020). In addition, many recall hearing anecdotal stories of friends or women at the same clinic having success after a large number of cycles. These anecdotal stories of success seem to play an influential role in fuelling hope and contribute to unrealistic expectations of IVF effectiveness. Whilst consumers scrutinise statistical information, narrative stories cause them to feel compelled (Jaramillo et al., 2019), illustrating the powerful influence of anecdotal stories. This study aims to explore - What is the influence of an anecdotal story of success against the odds despite contrasting statistical information on the low likelihood of success with another cycle of IVF - Does balancing anecdotes of success against anecdotes of failure attenuate their potential effects? Understanding the effect of anecdotal stories on medical decision making will help providers and consumers of IVF services be more aware of the impact anecdotal stories have. This could help patients make better-informed choices and encourage IVF providers to use anecdotes carefully and with caution.

Interventions

This study has two intervention arms and one control arm (so 3 arms in total), administered online using the Qualtrics survey software. The interventions will be delivered with paragraphs of text (hypothetical scenarios). The study will take approximately 15-20 minutes to complete. Interventional materials: a hypothetical scenario of a visit to an IVF specialist after six unsuccessful attempts of IVF. participants are asked to imagine they are now trying to decide whether to continue or stop IV

This study has two intervention arms and one control arm (so 3 arms in total), administered online using the Qualtrics survey software. The interventions will be delivered with paragraphs of text (hypothetical scenarios). The study will take approximately 15-20 minutes to complete. Interventional materials: a hypothetical scenario of a visit to an IVF specialist after six unsuccessful attempts of IVF. participants are asked to imagine they are now trying to decide whether to continue or stop IVF treatment. The scenario details the cost of another round of IVF, the time taken off work for appointments, and the emotional and physical toll the process takes on participants and their partners. The participant is told they have less than 5% chance of success with another round. Participants randomised to an intervention arm will then receive further information through anecdotal stories of success or failure. The two intervention arms consist of: A hypothetical scenario with a positive anecdote of success against the odds, or A hypothetical scenarios with both a positive and a negative anecdote (anecdote of failure) In the positive anecdote scenario, the IVF specialist will describe a story about a couple in a similar situation who tried once more and had success. In the paired positive and negative anecdote scenario, a story is told of a couple who had success with one more attempt, and of another couple who tried again for three more cycles and had no luck, with significant strain on their relationship and finances. The scenarios are included below: Exact hypothetical scenario text: Imagine that you have been undergoing in vitro fertilisation (IVF) with your partner for the past two years in attempts to conceive your first child. You have had six unsuccessful cycles to date, and are now trying to decide whether to continue or stop IVF treatment. Although most of the cost is covered by Medicare, each cycle has an out-of-pocket cost of around $5000. Each cycle requires you to take some time off work for appointments (e.g. ultrasounds, egg collection, embryo transfers). Treatment has also had an emotional and physical toll, as well as strained your relationship with your partner. With each failed cycle, you feel like you lose a piece of yourself, but the only way to get those pieces back is by having a baby. Although this process is incredibly difficult, having a baby is something you have always wanted and imagined for yourself. You have an appointment with your fertility specialist to discuss next steps. Your doctor says: “Although IVF is a long-term process and failed attempts are part of the process, success is most likely within five to six attempts. As you have now had six cycles of IVF, your chances of success with another cycle are less than 5%. Deciding to continue or stop is an incredibly difficult decision. [Positive anecdote] I had a couple with six very similar cycle results to you. They were despairing that they hadn’t had a successful pregnancy yet and were trying to work out if it was worth continuing. They decided to give it another go – and got pregnant! They’ve now got baby Oliver and are so glad they kept trying. [Paired positive and negative anecdotes] I’ve had two couples with six very similar cycle results to you. They were despairing that they hadn’t had a successful pregnancy yet, and were trying to work out if it was worth continuing. Both couples decided to give it another go - The first got pregnant! They’ve now got baby Oliver and are so glad they kept trying. But the other couple went on to have a further three cycles but sadly still had no luck. They’ve since stopped trying due to the strain it placed on their relationship and finances. I am happy to support you with whatever decision you decide.” Adherence to and/or fidelity of the intervention will be monitored through access to Qualtrics analytic data. Implausibly fast response times will be deleted and attention check question is included to ensure participants are paying attention to the study.

Sponsors

Sydney School of Public Health, The University of Sydney
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Caregiver)

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

Participants must be female, living in Australia, aged between 18-45 years

Exclusion criteria

n/a

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026