None listed
Conditions
Brief summary
Common after strenuous and unaccustomed exercise, exercise induced muscle damage (EIMD) typically results in soreness, inflammation, collagen breakdown and alterations in muscle function; these symptoms can impact sequent exercise performance and activities of daily living. As such, considerable research has been undertaken to identify modalities that can alleviate the symptoms of EIMD and expedite recovery, including various dietary interventions. Supplementation with dairy protein has shown promise in alleviating the symptoms of EIMD however, despite this growing evidence, there is no consensus as to the effect of dairy protein supplementation on recovery from EIMD. As an alternative to dairy protein, several recent studies suggest that supplementation with collagen hydrolysate, an inexpensive, protein rich by-product of the meat industry, may improve rates of recovery after eccentric exercise, while also enhancing adaptations to strenuous exercise. However, only a few studies have investigated the effect of collagen hydrolysate on recovery from EIMD and it appears that none have compared collagen hydrolysate to dairy protein. Therefore, the aim of this study is to investigate the effects of collagen hydrolysate on recovery from EIMD. Healthy male participants, aged between 18 and 40, will undertake a single trail in which they will complete a single 30-minute bout of downhill running at -15% incline at 70% of VO2max speed. Measures of muscle soreness, muscle function, running economy and blood markers of inflammation and muscle damage will be made prior to exercise and again 30 minutes, 24, 48 and 72 hours after exercise. Participants will consume either a supplement containing 25 g of protein from collagen hydrolysate, hydrolysed milk or a non-protein placebo powder 45 minutes, 22, 46 and 70 hours post-exercise. We hypothesise that, when compared to an equivalent amount of dairy protein or a placebo, collagen hydrolysate will reduce muscle soreness and inflammation and increase the rate of recovery for measures of muscle function.
Interventions
Participants will be given powder containing 25 g of protein from collagen hydrolysate, colouring and sweeteners or 25g of hydrolysed milk protein, colouring and sweeteners. The powder will be mixed with 250ml of water and consumed 45 minutes post-exercise and again 22, 46 and 70 hours post-exercise, along with a standardised meal. The approximate nutritional profile of the standardised meal is: 90g carbohydrate; 23g fat; 17g protein; 2904kJ.
The powder will be provided to participants in a plai
Participants will be given powder containing 25 g of protein from collagen hydrolysate, colouring and sweeteners or 25g of hydrolysed milk protein, colouring and sweeteners. The powder will be mixed with 250ml of water and consumed 45 minutes post-exercise and again 22, 46 and 70 hours post-exercise, along with a standardised meal. The approximate nutritional profile of the standardised meal is: 90g carbohydrate; 23g fat; 17g protein; 2904kJ. The powder will be provided to participants in a plain vacuum sealed sachet which will be marked with either A, B or C - neither the researchers nor the participants will know which treatment they are consuming. To ensure adherence to the intervention, participants will consume the first drink while at the laboratory and then be given the next days sachet at each subsequent visit to the laboratory. A text message will be sent each day to remind them to consume the powder, and meal.
Sponsors
Massey University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy, active males
Exclusion criteria
• If the individual undertakes regular (more than 3 times per week) strenuous exercise; this includes heavy resistance exercise or long duration/high intensity running. • If the individual is dairy/lactose intolerant (the hydrolysed milk powder is dairy based) • If the individual is vegetarian or vegan (as the supplements are made from animal products). • If the individual consumes a high protein diet (more than 25% of their daily energy comes from protein) and/or regularly consumes protein supplements. • If the individual regularly uses ergogenic supplements such as pre-workout products, branched chain amino acid (BCAA) powder, creatine monohydrate. • If the individual has an injury or medical condition that could be made worse by exercising or stops them from participating in high intensity exercise • If the individual has been ill in the 14 days before the study begins • If the individual is participating in another research trial
Outcome results
None listed