Clinical phenotypes and incidence of Anti-Neutrophilic Cytoplasmic Autoantibodies (ANCA) positive renal vasculitis in Queensland: The effect of environmental and occupational exposure

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12622000514707

Enrollment

160

Registered

2022-03-31

Start date

2022-04-11

Completion date

2022-09-26

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a retrospective multi-centre observational study that aims to determine the effect of environmental and occupational exposures on clinical phenotypes and incidences of ANCA positive renal vasculitis in Queensland.

Interventions

Adults who had a renal biopsy confirmed ANCA vasculitis will be invited to participate. Participants will have their data collected via questionaires, data collection from patient contact will include their past occupational history, environmental exposure to hazards including silica, dust, fumes, pesticides... There are no intervention planned in this study. Participants are required to complete questionnaires at enrolment only. Other data collected are from patient's medical records, including historic blood serological results, basic demographics, past treatment received and clinical response. Data will be collected via accessing in hopsital paper medical charts, Integrated Electronic Medical Records (ieMR) and Pathology Queensland database (AusLab/AusCare). These data are collected retrospectively covering study period of 2005-2021 and does not require any patient contact.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult patients whom had renal biopsy confirmed pauci-immune glomerulonephritis between 2005-2021

Exclusion criteria

Nil

Outcome results