Effects of polyherbal mouthwash versus 0.2% Chlorhexidine mouthwash on patients for dental plaque, gingivitis, and gingival bleeding in Faisalabad, Pakistan: A randomized comparative clinical trial..

Effects of polyherbal mouthwash versus 0.2% Chlorhexidine mouthwash on patients for dental plaque, gingivitis, and gingival bleeding in Faisalabad, Pakistan: A randomized comparative clinical trial.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12622000421730

Enrollment

Registered

2022-03-14

Start date

2022-06-01

Completion date

2022-06-07

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is aimed for assessment of a herbal mouthwash on patients with dental plaque, gingivitis, gingival bleeding and its action comparison with standard 0.2% chlorhexidine mouthwash. The study is designed as prospective, double blinded, randomized, active controlled clinical trial. The endpoints will measured two times during the study, first at start, and second at finalizing. The in-vitro tests shall also be conducted to confirm anti-bacterial activity of product in comparison to standard product.

Interventions

The subjects in intervention arm shall receive herbal mouthwash, the product under test. Subject will be counseled to take 10ml of the mouthwash and rinse mouth with it for 1 minute, after brushing teeth. The frequency will be once daily at night for 30 days. The herbal mouthwash will contain essential oil extracts of clove, cardamom, cinnamon, peppermint leaves and fennel, and aqueous extracts of neem and miswak. The adherence shall be monitored by counting the returned of unused mouthwash

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Patient with dental plaque and gingivitis 2. Patient with at least 28 teeth 3. Patient above age of 18 years 4. Patient below age of 70 years 5. Patient capable of giving consent

Exclusion criteria

1. Smokers & narcotic addicts 2. Pregnant and lactating patients 3. Patients taking anti-platelets and anti-coagulant medications 4. Foreign nationals 5. Patients having other infections 6. Patients having any disorders related to blood clotting 7. Dementia

Outcome results