None listed
Conditions
Brief summary
Multiple myeloma is still an incurable hematological neoplasm, which mainly affects the elderly. Neoplastic plasmocytes produce a monoclonal protein that causes a number of various organ-related consequences. Additionally, in the bone marrow microenvironment, bone tissue destruction associated with the activity of neoplastic cells occurs. Patients very often avoid physical activity due to fear of injury, which leads to progressive immobilization. In this study, patients participate in a cycle of 6-week Nordic walking trainings. The aim of this trial is to assess the impact of this type of training on the biochemical parameters of blood and functional efficiency of multiple myeloma patients. We assume that the conducted trainings will contribute to the improvement of the assessed parameters and to a deeper understanding of the impact of physical activity on multiple myeloma patients.
Interventions
Nordic walking (NW) training sessions are performed in groups for 6 weeks, 3 times a week, in the morning, at University of Physical Education in Krakow by a qualified instructor. Before the first training session, the length of the poles is adjusted for each participant individually. The participants are also acquainted with the correct walking technique, which is monitored and adjusted in each participant during the trainings. Heart rate is controlled individually in each participant with use
Nordic walking (NW) training sessions are performed in groups for 6 weeks, 3 times a week, in the morning, at University of Physical Education in Krakow by a qualified instructor. Before the first training session, the length of the poles is adjusted for each participant individually. The participants are also acquainted with the correct walking technique, which is monitored and adjusted in each participant during the trainings. Heart rate is controlled individually in each participant with use of sport-tester watch. Each session consists of a 10-minute warm-up. The main part is 45 minutes long and consists of a practice with poles and walking with the correct Nordic walking technique. The walking time is extended with each training session, until it reached a maximum of 45 minutes. At the end, a 5-minute calming part is performed (calming and stretching exercises). Attendance of participants in training sessions is monitored with use of a session attendance checklist (required attendance: over 80%).
Sponsors
Olga Czerwinska-Ledwig, PhD
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Multiple myeloma in plateau stage, without cytostatic treatment • Acceptable bisphosphonate therapy • General good condition of the patient (ECOG scale: 0,1,2) • No contraindications to participate in health training • Cardiovascular capacity on the NYHA scale 1-2 • No chronic respiratory diseases • No other neoplastic disease
Exclusion criteria
• Active anti-cancer treatment • Significant liver and kidney damage • High hypercalcemia • An infectious disease • Acute respiratory infections • Fall from own height complicated with limb and torso trauma during the project duration
Outcome results
None listed