None listed
Conditions
Brief summary
The term supraglottic constriction describes excessive tension in the muscles surrounding the larynx (voice box). This is commonly seen in individuals with voice disorders such as Muscle Tension Dysphonia, but may also occur in those without any voice impairment. Despite its common occurrence, assessment methods are limited. Typically, assessment uses a flexible camera (endoscope) that is inserted into the throat, which allows these muscles to be directly observed. During the endoscopic examination, the severity of constriction is usually judged subjectively using labels such as "mild", "moderate" or "severe". However, severity of constriction is not well defined, leading to low reliability of assessment. This study aims to investigate several methods of assessing muscle tension in the throat. The first method that will be investigated is a software that uses novel objective measures to assess constriction on endoscopic images and videos of the throat. These measures will be compared to subjective methods of quantifying tension and audio recordings of the voice. The second method that will be studied is high-density surface electromyography (sEMG) that will be used to measure activity of the throat muscles from the skin surface. Muscle activation patterns will be compared to endoscopic data to determine the relationship between levels of muscle activity and observable muscle tension.
Interventions
This is a two-phase study. Phase 1 - 25 participants (20 with MTD, 5 controls) will be recruited. They will be required to attend a single data collection session that will take up to one hour. All participants will undergo the following: 1) voice assessment (approx. 3 minutes long; sustained production of vowel sound "ee", repetition of the sentence "how hard did he hit him?", and humming), audio will be recorded using a microphone attached to clothing; 2) assessment using flexible endoscopic imaging inserted through the nose and into the throat, including a repeated voice assessment (approx. 5 minutes long; sustained production of vowel sound "ee", repetition of the sentence "how hard did he hit him?", and humming) with endoscope in situ; 3) high-resolution surface electromyography (sEMG; placed on the skin overlaying the neck, approx. 10 minutes to fit) will then be used during a further repetition of the voice assessment (approx. 3 minutes long; sustained production of vowel sound "ee", repetition of the sentence "how hard did he hit him?", and humming); 4) flexible endoscope will be re-placed into the throat (simultaneously with sEMG) and a final voice assessment will be completed (approx. 5 minutes long; sustained production of vowel sound "ee", repetition of the sentence "how hard did he hit him?", and humming). The assessment will be run by a Speech-Language Therapist/PhD student. Phase 2 5 Speech-Language Therapists (SLT) will be provided with de-identified still images and video files gathered during Phase 1 of the study. The SLTs will use two different methods (subjective and objective software) to measure the amount of muscle tension in the laryngeal muscles. The software is newly developed by members of the research team, and is as yet un-named. The SLTs will use the software to gather objective measurements by measuring number of pixels in endoscopic still images and videos. To do this, the SLTs will measure vocal fold length and width (at anterior 1/3 and halfway point of the vocal folds), which the software will use to calculate total pixel value. Total pixel value will quantify visible vocal fold as an indicator of muscle tension. To determine subjective measures, the SLTs will rate constriction using a scale (0 - no constriction, 1 - mild constriction, 2 - mild-moderate constriction, 3 - moderate constriction, 4 - moderate-severe constriction, 5 - severe constriction, 6 - complete constriction/no visibility of the vocal folds). Participation in this phase of the study will take up to four hours in total. This does not need to be completed in one go, but will need to be completed within one week.
Sponsors
Study design
Eligibility
Inclusion criteria
Phase 1 MTD group: - 18 years or older - Able to give informed consent - Diagnosed with MTD following an endoscopic voice assessment by an otolaryngologist and Speech-Language Therapist Healthy group: - 18 years or older - Able to give informed consent Phase 2: - 18 years or older - Able to give informed consent - Currently practicing as a Speech-Language Therapist in New Zealand - Currently working with patients with voice disorders - Current or recent (last six months) experience with interpreting laryngeal examinations on endoscopy/stroboscopy
Exclusion criteria
MTD group: - Lack of observable supraglottic constriction (muscle tension) during diagnostic examination - Presence of organic lesions or vocal fold pathology e.g. tumours, nodules or polyps - Smoking or vaping in the last 6 months - Upper respiratory tract infection (URTI) in the last 2 weeks Healthy group: - Current or historic voice disorders - Acute loss or impairment of voice in the last month e.g. acute laryngitis - Smoking or vaping in the last 6 months - Upper respiratory tract infection in the last 2 weeks