Skip to content

ProSed Australasia: A database of procedural sedation practices and outcomes in Australasian Emergency Departments

ProSed Australasia: A database of procedural sedation performed in Australasian Emergency Departments for analysis of the interaction between medications used, doses used, adverse events, procedure success rates, and outcomes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12622000095763
Enrollment
644
Registered
2022-01-24
Start date
2021-12-10
Completion date
2041-12-31
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Procedural sedation involves the administration of sedative medications to facilitate a painful or intolerable procedure. It is commonly performed in emergency departments for reduction of a range of orthopaedic injuries, to facilitate cardioversion for tachyarrhythmias, amongst other uses. The usual practice involves one clinician performing sedation, another clinician performing a procedure, and a nurse assisting with medications, monitoring and documentation. It is generally performed in a resuscitation bay to be prepared for any complications that may arise. Procedural sedation is commonly performed in Australasian emergency departments however the evidence base for the practice of it is not as robust as many other areas. Drugs used for procedural sedation have changed over time with introduction of newer agents, however there remains a lack of evidence as to best practices. As such the administration of procedural sedation varies widely with significant variation within departments and even wider variation internationally. We are establishing a database of all procedural sedation performed at our hospital with a view to expanding this database state-wide and eventually throughout Australasia. This large dataset will allow us to analyse the sedation performed and draw associations between the patients involved, the medications used, adverse events, and procedure success rates.

Interventions

Our registry will include all patients undergoing procedural sedation in the emergency department at the involved sites. The observation will continue until the end of the sedation once the patient is waking up, less than an hour. Information will be recorded regarding the indication for sedation, where it was performed, who performed it, patient weight, American Society of Anesthesiologists (ASA) grade, medications given for the procedure, adverse events, management required, deepest level of s

Our registry will include all patients undergoing procedural sedation in the emergency department at the involved sites. The observation will continue until the end of the sedation once the patient is waking up, less than an hour. Information will be recorded regarding the indication for sedation, where it was performed, who performed it, patient weight, American Society of Anesthesiologists (ASA) grade, medications given for the procedure, adverse events, management required, deepest level of sedation achieved, and disposition. Data will be entered into a form by the clinician performing the procedure, to happen as soon as possible after the procedure takes place. Data will be collected for 20 years.

Sponsors

Northern Sydney Local Health District
Lead SponsorGovernment body

Eligibility

Sex/Gender
All
Healthy volunteers
No

Inclusion criteria

All patients undergoing procedural sedation at a participating site.

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026