Queensland Renal Biopsy Registry Sub Study: Multi-centre prospective observational cohort study investigating association between anti-neutrophil cytoplasmic antibodies (ANCA) results and relapse of ANCA associated vasculitis

Multi-centre prospective observational cohort study investigating association between anti-neutrophil cytoplasmic antibodies (ANCA) results and relapse of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12622000012774

Enrollment

Registered

2022-01-11

Start date

2021-05-13

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This prospective study will monitor ANCA levels in patients with ANCA vasculitis. The purpose of this study is to Identify if ANCA rises are associated with relapse of ANCA vasculitis. Study hypothesis: two and four-fold ANCA rises will precede clinical relapses within the prior 6 months

Interventions

3 monthly assessments for at least 3 years. Monitoring association between ANCA levels and disease activity / relapse. - No alteration to patient standard medical care - However, patient medical records will be accessed - long-term (many years) 3 monthly follow up will be required for disease management irrespective of enrolment in trial

Eligibility

Sex/Gender

All

Healthy volunteers

Inclusion criteria

Patients with ANCA vasculitis based on compatible serology, radiology, histology and/or biochemistry. Participants need to have been enrolled into the Queensland Renal Biopsy Registry

Exclusion criteria

ANCA negative vasculitis

Outcome results