None listed
Conditions
Brief summary
Sun damage caused photo-aging that results in wrinkles causing concern to the individuals who often seek medical or cosmetic treatments. This study aims to compare the efficacy of No-Tox, a commercially available proprietary plant-and-plankton based cosmeceutical formulation vs. a prescription-grade pharmaceutical formulation ( 0·05 mg/g Tretinoin) in improving the appearance of facial wrinkles.
Interventions
No-Tox serum (manufactured under license by Smoothe Inc, DE, USA) will be applied twice daily over wrinkled areas of the face (4-5 drops twice daily as recommended by the manufacturers). The cosmetic formulation contains plukenitia volubis, niacinamide, hyaluronic acid and plankton extracts (detailed ingredient list under documents) Measurements and clinical reviews will be undertaken at 1-month and 3-month periods on healthy adult volunteers. The amount of product provided has been estimated to
No-Tox serum (manufactured under license by Smoothe Inc, DE, USA) will be applied twice daily over wrinkled areas of the face (4-5 drops twice daily as recommended by the manufacturers). The cosmetic formulation contains plukenitia volubis, niacinamide, hyaluronic acid and plankton extracts (detailed ingredient list under documents) Measurements and clinical reviews will be undertaken at 1-month and 3-month periods on healthy adult volunteers. The amount of product provided has been estimated to last 3 months at which the empty containers will be returned.
Sponsors
Skin Surgery Clinic
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy volunteers, aged between 25 and 75 without acute or chronic skin diseases will be enrolled.
Exclusion criteria
Anyone with skin diseases, acute or chronic, those unable to provide informed consent, or those with a history of allergies or sensitivities to any of the ingredients in the study products. For females, pregnancy (or planned pregnancy during he study period) will also be an exclusion.
Outcome results
None listed