None listed
Conditions
Brief summary
Whilst high-grade atrioventricular block (HGAVB) occurs in a significant proportion of patients after transcatheter aortic valve implantation (TAVI), there are currently no sensitive and specific methods for predicting this adverse outcome. This study aims to determine the utility of both novel and previously published electrophysiological predictors of HGAVB including rapid right atrial pacing and HV interval testing before and after TAVI. This study will use implantable loop recorders to detect delayed HGAVB after TAVI.
Interventions
This study will investigate the factors associated with high grade atrioventricular block (HGAVB) occurring up to 24 months after Transcatheter Aortic Valve Implantation (TAVI). Electrophysiology testing (including AV Wenckebach and HV interval measurement) will be performed immediately prior to and after TAVI deployment. All patients who do not require insertion of a permanent pacemaker during their admission will receive an implantable loop recorder (which is part of the study, additional to s
This study will investigate the factors associated with high grade atrioventricular block (HGAVB) occurring up to 24 months after Transcatheter Aortic Valve Implantation (TAVI). Electrophysiology testing (including AV Wenckebach and HV interval measurement) will be performed immediately prior to and after TAVI deployment. All patients who do not require insertion of a permanent pacemaker during their admission will receive an implantable loop recorder (which is part of the study, additional to standard of care, and will remain implanted after the study unless there is an indication for removal). Patients will be followed up at 28 days, 3 months, 6 months, 12 months and 24 months for loop recorder / pacemaker interrogation, ECG, TTE and medical review.
Sponsors
Royal North Shore Hospital, Northern Sydney Local Health District
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age >= 18 years 2. Undergoing elective TAVI and have a scheduled date 3. Willingness to give written informed consent
Exclusion criteria
1. Permanent Pacemaker 2. Valve-in-valve TAVI
Outcome results
None listed