None listed
Conditions
Brief summary
The purpose of this research is to examine the effects of protein supplements on serotonin levels, mood, cognition, fatigue, sleepiness and parameters of muscle strength. Your participation will involve: 3 morning testing sessions of ~ 3 hours each to the Exercise Physiology Research Laboratory at QUT, Kelvin Grove campus. Each visit will consist of questionnaires of sleepiness, mood, cognition, neuromuscular testing on your calf muscles, the consumption of a supplement and repeating all testing plus performing a muscle fatigue protocol.
Interventions
In this project, we will study the effects of protein-based supplements ( 40 g of Alpha-lactalbumin and zein, mixed with 500 ml of vegetable juice) on sleepiness, mood, cognition, fatigue and parameters of motor function. Participants will be asked to come to the laboratory in QUT Kelvin Grove for three visits of ~4 hours each (three testing sessions: 1 placebo and 2 intervention supplement sessions) where they will be given a supplement and neuromuscular, psychological and dietary assessments w
In this project, we will study the effects of protein-based supplements ( 40 g of Alpha-lactalbumin and zein, mixed with 500 ml of vegetable juice) on sleepiness, mood, cognition, fatigue and parameters of motor function. Participants will be asked to come to the laboratory in QUT Kelvin Grove for three visits of ~4 hours each (three testing sessions: 1 placebo and 2 intervention supplement sessions) where they will be given a supplement and neuromuscular, psychological and dietary assessments will be performed. Sessions will be separated by at least 1 week wash-out period. This will be a randomised double-blind cross over study. The results of this research will contribute to the understanding of the effects of serotonin on sleepiness, mood, cognition, motor function and fatigue. Most importantly, this study will test the feasibility of using food as a strategy for modifying neurotransmitter levels and its influence on psychological parameters, muscle fatigue and strength development. The supplement protocol is based on a previous research study by Fernstrom 2013 (https://doi.org/10.1016/j.clnu.2012.11.027). All sessions will be delivered by a PhD student with background in Nutrition and exercise testing and supervisor briefing in neuromuscular assessments.
Sponsors
Karen Mackay
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
non-smokers, BMI <30 kg/m2.
Exclusion criteria
Musculoskeletal disorders that limit performance in the assessed limb; diagnosed neurological disorders (e.g. amyotrophic lateral sclerosis or ALS); diagnosed serotonergic disorders (e.g. depression); consumption of drugs that affect serotonin and noradrenaline release (e.g. recreational drugs, SRRIs or antidepressants); diagnosed Vitamin D or B6 deficiency; diagnosed with high cholesterol; diagnosed with iron anaemia deficiency. Women must not be pregnant, breast feeding or menopausal.
Outcome results
None listed