Gastroparesis symptoms and its treatment using low-viscosity soluble dietary fibres

Each participant clinical study involved a total of four interventions (Over the course of four weeks). All interventions were given under supervised administration (Face-to-Face) at the MacArthur Clinical School, Western Sydney University (WSU), Campbelltown, NSW 2560, Australia. Each intervention session included a supervised 3.5 hours monitoring period where measurements were taken. Interventions were delivered to participants by Harsha Suresh (Co-Investigator, PhD Candidate) under the supervision of Dr. Vincent Ho (Co-Investigator, Clinical Gastroeneterologist) and Dr. Jerry Zhou (Principal Investigator, Clinical Scientist). The four interventions were Water (200 mL) as a negative control baseline and dietary fibres supplements (10 g in 200 mL) of Partially-hydrolysed guar gum (PHGG), Gum Arabic and Psyllium Husk. Psyllium Husk was assigned as the positive control. Each intervention was followed by the supplementation of Actilax (10 mL) and a glucose challenge (50 grams in 300 mL). Each intervention (Water, PHGG, Gum Arabic & Psyllium Husk) was delivered only once for each participant. The interventions were spaced 1-week apart from each other. The negative control (Water) intervention was given on Week 1 followed by dietary fibre interventions in Weeks 2, 3 & 4. The dietary fibre interventions (PHGG, Gum Arabic & Psyllium Husk) were given in randomized order (The order of dietary fibre interventions was different for each participant).