None listed
Conditions
Brief summary
Chronic kidney disease (CKD) and cardiac disease are two significant health conditions that can influence a woman’s pregnancy, however little is known about their prevalence and health impact within the South Australian population. These pregnancies are associated with significant risks of morbidity and mortality and propose a challenge to clinicians who manage them. The aim of this study is to prospectively record the incidence, prevalence, etiology, outcomes and follow up of maternal chronic diseases in the obstetric population of South Australia. This is a prospective cohort study of pregnant women with acquired or chronic cardiac or kidney disease.
Interventions
This study will prospectively record the incidence, prevalence, etiology, outcomes, and follow up of maternal cardiac disease and chronic kidney disease (CKD) in the obstetric population of South Australia. No active participation will be required to participate in this study, as only clinical data from medical records will be collected. Not additional testing or interventions are required for participants. After the index pregnancy, participants will be contacted for follow-up annually for ten
This study will prospectively record the incidence, prevalence, etiology, outcomes, and follow up of maternal cardiac disease and chronic kidney disease (CKD) in the obstetric population of South Australia. No active participation will be required to participate in this study, as only clinical data from medical records will be collected. Not additional testing or interventions are required for participants. After the index pregnancy, participants will be contacted for follow-up annually for ten years postpartum.
Sponsors
Margaret Arstall
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1) Are pregnant AND 2) Present with at least one of the following: a. Congenital cardiac disease b. Valvular heart disease c. Cardiomyopathy d. Ischaemic heart disease e. Arrhythmia f. Pulmonary hypertension g. Aortic pathology h. Pre-conception diagnosis of CKD of any stage (including dialysis and transplant recipients) i. Newly identified kidney impairment in pregnancy, defined by any one of the following: -Two or more serum creatinine readings above the normal local laboratory reference range for pregnancy -Significant proteinuria during pregnancy (urine PCR> 30 mg/L), not in the context of pre-eclampsia j. Strong clinical suspicion of underlying CKD in women with acute kidney injury or other comorbidity
Exclusion criteria
• Physiological palpitations of pregnancy • Sinus tachycardia without evidence of other cardiac disease • Pre-eclampsia with proteinuria, but no other features or clinical suspicion of underlying kidney disease or kidney impairment • Uncomplicated hypertension with no other features of kidney disease
Outcome results
None listed