None listed
Conditions
Brief summary
Oesophageal soft food bolus obstruction (SFBO) is a common gastroenterological presentation. Mentha piperita, the active component of peppermint oil has been proposed as an adjunct in SFBO. This study is to evaluate the effectiveness of Mentha Piperita in facilitating spontaneous passage of SFBO and improving effectiveness of the endoscopic push technique, via a prospective randomised control trial. To check effectiveness of peppermint oil in relieving blockage from food stuck in the food pipe.
Interventions
Patients presenting with food bolus, will have endoscopy performed by a gastroenterologist or gastroenterology trainee under the supervision of a gastroenterologist.
Patient with food bolus distance > 20 cm from incisors will be randomized to receiving either the study drug (2%peppermint oil) or placebo. This will be instilled at an initial volume of 10mls and delivered endoscopically, followed by a further 10mls one minute later if there is no spontaneous resolution of the food bolus. Should th
Patients presenting with food bolus, will have endoscopy performed by a gastroenterologist or gastroenterology trainee under the supervision of a gastroenterologist. Patient with food bolus distance > 20 cm from incisors will be randomized to receiving either the study drug (2%peppermint oil) or placebo. This will be instilled at an initial volume of 10mls and delivered endoscopically, followed by a further 10mls one minute later if there is no spontaneous resolution of the food bolus. Should there be no spontaneous passage of SFBO one minute after the second administration then a gentle push technique will be trialled. If the push technique fails, then retrieval of the SFBO will be using equipment at the discretion of the endoscopist. The total duration of the endoscopy is one of the end points that will be measured. Should the peppermint prove successful then the duration of endoscopy in the study arm will be significantly shorter. Difficult food bolus obstruction can sometimes take over 2 hrs to disimpact. Adherence to intervention will be monitored by documentation during procedure.
Sponsors
Logan Hospital, Logan Gastroenterology Unit
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All patients presenting to Logan hospital, 18 years of age with an oesophageal food bolus obstruction will be considered for the study.
Exclusion criteria
Patients who are unable to consent for themselves, those who are pregnant, those with documented stricture, oesophageal mass lesion or Schatzki ring, or those with suspected hard food bolus obstruction or foreign body will be excluded.
Outcome results
None listed