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The effect of resistance training prescription on muscle strength and health.

Are muscle strength and health improvements associated with the dose of resistance training in healthy untrained adults?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12621001501831
Enrollment
105
Registered
2021-11-04
Start date
2022-01-03
Completion date
2022-10-14
Last updated
2023-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this project is to examine the changes in muscle strength with different prescriptions of RT volume and intensities while equating the overall resistance training ‘dose’ in healthy untrained adults. Resistance training dose is calculated as the number of sets × repetitions × intensity × number of exercises. This investigation will also examine how muscle strength is impacted when an intervention group is prescribed roughly half the dose of RT. In addition, this study looks to determine if RT dose influences changes in health and well-being. Lastly, this study will examine the relationship between objectively determined intensity and perceived intensity of training over multiple sets and exercises. The researchers hypothesize that no significant difference in muscle strength will be observed between the two equated RT dose interventions, with the reduced dose intervention producing significant increases in muscle strength but lower when compared to the other intervention groups.

Interventions

Participants will undergo an 8-week resistance training (RT) intervention where they will attend the La Trobe University, Bendigo Campus three days per week which will be separated by a 48-hour recovery period. The intervention will be administered individually, although multiple participants might be completing the intervention at the same time. The RT sessions will be supervised by qualified personal with previous experience in implementing RT programs (exercise scientist, exercise physiologis

Participants will undergo an 8-week resistance training (RT) intervention where they will attend the La Trobe University, Bendigo Campus three days per week which will be separated by a 48-hour recovery period. The intervention will be administered individually, although multiple participants might be completing the intervention at the same time. The RT sessions will be supervised by qualified personal with previous experience in implementing RT programs (exercise scientist, exercise physiologist, strength and conditioning coach), some of which will be members of the research team. The duration for each RT session will be approximately 50 minutes. All exercise sessions will be completed under supervision to allow adherence to the intervention to be assessed and monitored. The RT dose (sets × repetitions × number of exercises × intensity) has been equated between the two intervention groups, with the variation in the prescribed RT dose being 2.8%. Two ‘high dose’ RT interventions will be prescribed, the details of each intervention are provided below. Intervention Group One: 50% 1RM, 2-sets of 14-repetitions across 6-exercises (bench Press, 45° leg press, smith machine seated overhead press, barbell biceps curl, calf raise, lat pulldown), 3-minutes rest between sets and exercises. Total dose of RT = 8400. Intervention Group Two: 80% 1RM, 3-sets of 6-repetitions across 6-exercises (bench Press, 45° leg press, smith machine seated overhead press, barbell biceps curl, calf raise, lat pulldown), 3-minutes rest between sets and exercises. Total dose of RT = 8640.

Sponsors

La Trobe University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1) Male and females aged 18-65 years old. 2) Individuals not regularly performing resistance training.

Exclusion criteria

1) Individuals performing resistance training more than once per week for the previous 6-weeks. 2) Individuals who are pregnant or within 12-months post-partum. 3) Individuals with severe movement or coordination disorders. 4) Individuals with cognitive impairments, or unable to understand written and verbal English. 5) Individuals consuming pre-workout and protein supplements. 6) Individuals who have contraindications to performing resistance exercise.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026