Skip to content

Fasting and interruption to enteral nutrition delivery in critically ill patients

Fasting and interruption to enteral nutrition delivery in Australian critically ill patients: an observational study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12621001477819
Acronym
NUTRIENT-Fasting
Enrollment
134
Registered
2021-10-28
Start date
2021-06-28
Completion date
2021-10-08
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Critically ill patients are often unconscious and require airway support via a mechanical ventilator. This renders them able to eat, with nutrition most commonly provided by a gastric feeding tube (termed enteral nutrition [EN]) in the Intensive Care Unit (ICU). EN feeding interruptions are common in the ICU and may significantly impact nutrition delivery, with approximately 50-60% of energy and protein targets delivered in practice. Reasons for EN feeding interruptions are varied and may include fasting for airway procedures, including tracheal extubation (i.e. removal of the breathing tube used for ventilation). There is limited contemporary information on reasons for EN feeding interruptions in Australian ICUs, including the number of hours fasted prior to tracheal extubation. We are conducting an observational study (NUTRIENT-Fasting) using a pre-existing dataset from NUTRIENT (Nutrition practice in critically ill adults – an observational study; ACTRN12620001025921) to assist to better understand the current reasons for EN interruptions over the first seven days of ICU admission in critically ill patients that received mechanical ventilation and EN across 35 of the Australian ICU sites included in NUTRIENT.

Interventions

Enteral nutrition (EN) is the most preferred and common method of nutrition provision in mechanically ventilated, critically ill patients. However, EN feeding interruptions are common in the Intensive Care Unit (ICU) and can significantly impact EN provision. Contemporary data in Australia is needed to better understand the frequency and most common reasons for EN feeding interruptions and associations with nutrition adequacy. NUTRIENT-Fasting is an observational study of EN practices in mech

Enteral nutrition (EN) is the most preferred and common method of nutrition provision in mechanically ventilated, critically ill patients. However, EN feeding interruptions are common in the Intensive Care Unit (ICU) and can significantly impact EN provision. Contemporary data in Australia is needed to better understand the frequency and most common reasons for EN feeding interruptions and associations with nutrition adequacy. NUTRIENT-Fasting is an observational study of EN practices in mechanically ventilated, critically ill adults recruited from 35 Australian ICUs through secondary analysis of the NUTRIENT dataset (Nutrition practice in critically ill adults – an observational study (ACTRN12620001025921)). The aim of this study is to report on EN fasting practices and delivery over the first 7 days of ICU admission in mechanically ventilated, critically ill patients. No additional participants will be enrolled and there will be no active participant involvement. Routinely collected data will be obtained from medical records. This study will access the NUTRIENT dataset, the variables extracted include: 1) Patient level data: patient demographics, duration of EN cessation prior to tracheal extubation, reasons and duration from all EN interruptions, nutrition prescription and delivery. 2) Site level data: ICU sites with and without fasting guidelines prior to extubation, reported duration in hours recommended for EN cessation (where applicable). 3) Outcome data: duration of mechanical ventilation, number of surgeries, duration of ICU and hospital stay.

Sponsors

Dr Emma Ridley
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

We will include recruited patients from NUTRIENT (ACTRN12620001025921) for the first seven days of ICU admission that received: - EN on any of the seven day study period; - Invasive mechanical ventilation received during the study period.

Exclusion criteria

Received more than four days of Parenteral Nutrition (PN) in the seven day study period

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026