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Evaluating the effect of an emergency department protocol and early outpatient follow up in a specialised clinic for atrial fibrillation

Redesigning care with an Emergency Department protocol and rapid access clinic: Can this reduce hospitalisations for Atrial Fibrillation?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12621001466831
Acronym
REDUCE AF
Enrollment
458
Registered
2021-10-27
Start date
2023-08-30
Completion date
2024-07-01
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Atrial fibrillation (AF) is a global epidemic associated with significant morbidity and mortality and growing health care burden. Hospitalisations due to AF are the most common cause for cardiovascular hospitalisation in Australia, many of which are preventable. Redesigning care delivery could result in fewer unnecessary hospitalisations and complications related to this condition, such as stroke, the most devastating yet often preventable complication of AF. Whilst effective medications can be used to reduce the risk of stroke, these are frequently under or overused, resulting in suboptimal care delivery. The use of protocols in the emergency department (ED) to guide clinicians in the acute management of AF has resulted in a marked reduction of hospitalisations related to AF in other countries, yet has never been tested in an Australian setting. This study seeks to evaluate an innovative model of care for the acute management of AF, combining an emergency department protocol with early outpatient follow up in a nurse led rapid access AF clinic. This will ensure standardised and guideline adherent care delivery to reduce the risk of preventable hospitalisations and complications in the AF population. We believe that this model of care will help to reduce unnecessary hospital admissions for AF, in addition to reducing complications associated with the condition and empowering individuals to learn how to self manage their AF.

Interventions

There are two components to the intervention: 1. An emergency department protocol for the management of atrial fibrillation (AF). This protocol will aim to guide emergency department clinicians in the acute management of AF to standardise care delivery, provide appropriate anticoagulation to reduce stroke risk and written advice for patients on management of the current or recurrent episodes of AF. This emergency department protocol has been developed by a multidisciplinary team including elect

There are two components to the intervention: 1. An emergency department protocol for the management of atrial fibrillation (AF). This protocol will aim to guide emergency department clinicians in the acute management of AF to standardise care delivery, provide appropriate anticoagulation to reduce stroke risk and written advice for patients on management of the current or recurrent episodes of AF. This emergency department protocol has been developed by a multidisciplinary team including electrophysiologists, emergency department physicians, emergency department nurses and specialist atrial fibrillation nurses. The protocol has been presented and refined following presentation to a specialist group of electrophysiology researchers (Centre for Heart Rhythm Disorders) and the emergency department team at the Royal Adelaide Hospital. The protocol will be evaluated at the same time as the rapid access AF clinic, as this clinic is an integral part of the protocol. 2. All intervention participants will be asked to return to the hospital within 24-72 hours from their emergency department presentation to attend a rapid access AF clinic. This clinic will be staffed by a specialist cardiology nurse and electrophysiology fellow or consultant. The nurse will receive training in the use of structured educational visiting, a technique designed to educate and empower the patient with use of key messages deemed essential to facilitate self management of their condition. Delivery of this education will be supported by a validated written patient resource, Living Well with Atrial Fibrillation. This resource was previously developed and evaluated in another research study undertaken by our group (Home Based Education and Learning Program for Atrial Fibrillation) and was published in 2019. In addition to this education, other care provided in this clinic will include referral for electrical cardioversion (if required), referral for other investigations in these have not been performed in the last 12 months, including holter monitoring, echocardiography, blood testing and exercise stress testing and provision of advice for the future management of AF episodes. The appropriate use of medication to manage AF, including oral anticoagulation to manage stroke risk and rate and rhythm controlling agents will be prescribed as required. Relevant comorbidity management will also be assessed with referral to other healthcare professionals permitted if indicated. This initial visit will be followed up by one follow up visit four to six weeks later to re-enforce education provided and review any test results. The initial visit is expected to last for 60-90 minutes with the second visit expected to take 30-60 minutes. Following this second visit, care will be returned to the treating General Practitioner and Cardiologist. A letter will be sent to the General Practitioner and Cardiologist summarising each visit. If patients re-present to hospital with atrial fibrillation or flutter over follow up, they will be managed with the emergency department protocol if they meet the inclusion and exclusion criteria. One extra follow up visit will be undertaken in the rapid access AF clinic to address any potentially modifiable factors associated with repeat hospital presentations. This will be scheduled to occur within 24-72 hours as per the standard protocol. Adherence to the protocol will be evaluated through audit of medical records. This will be recorded in the research database. Adherence to the rapid access AF clinic protocol will be ensured through practitioner training and oversight by senior research members. A checklist will be utilised in the research database to ensure that all required clinic components are adhered to.

Sponsors

Central Adelaide Local Health Network
Lead SponsorGovernment body

Study design

Allocation
Non-randomised trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

• All individuals aged 18 years of age or older and 90 years of age or younger presenting to the emergency department predominantly due to AF • AF or atrial flutter documented on ECG or rhythm strip during hospital presentation • Living independently

Exclusion criteria

• Age less than 18 years and greater than 90 years of age • Absence of ECG documentation of AF during index presentation • Acute heart failure or acute coronary syndrome on index presentation to ED with AF • Documented thyrotoxicosis or acute pneumonia at index presentation • Known left ventricular ejection fraction <35% • Complex congenital heart disease and patients with Wolff-Parkinson-White syndrome • Cardiac surgery < 2 months prior to index presentation • Patients with a terminal malignancy or any condition with <12months life expectancy • Stage IV or V chronic kidney disease/dialysis (ie eGFR < 30 mL/min) • Pregnancy • Poor English literacy • Non-independent living • Inability to provide informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026