None listed
Conditions
Brief summary
32 healthy, fit men aged 18-45 years, with running as one component of their exercise regime will be recruited to receive daily supplementation of probiotics or placebo for 4 weeks. Then the effect on running time trial in the heat will be measured. This is a randomised cross-over design so that men will start either the treatment or placebo in the first phase and then continue with the control or treatment for the second phase of the study, so that all participants complete both phases, but in random order. Mucosal immunity will be determined by IgA in saliva by collection of saliva following the time trial.
Interventions
4 weeks of daily supplementation of NZMP PREP capsule containing 12 billion CFU probiotics. 3 weeks washout between cross-over conditions.
Sponsors
Fonterra Co-operative Group Limited
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver)
Eligibility
Sex/Gender
Male
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy, fit men aged 18-45 years. With running as one component of their exercise regime
Exclusion criteria
Non-smokers, no antibiotics, probiotic supplements, or select fermented dairy for 3 weeks.
Outcome results
None listed