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Changes in the Autonomous Nervous System and in the cranio-facial pain threshold after applying visceral manual therapy in patients with chronic migraine and functional gastrointestinal disorders.

Changes in the Autonomous Nervous System and in the cranio-facial pain threshold after applying visceral manual therapy in patients with chronic migraine and functional gastrointestinal disorders.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12621001381875
Enrollment
2
Registered
2021-10-11
Start date
2021-04-09
Completion date
2023-12-31
Last updated
2022-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The objective is to assess the changes produced by manual visceral treatment in a homogeneous group of patients with chronic migraine and functional gastrointestinal disorders. These changes produced will be measured at the level of the Autonomous Nervous System (heart rate variability), in cervical mobility, sensitive threshold and in the pressure pain threshold on the sutural cranial point, a neural point (Valleix supraorbital neural point ) and a muscular trigger point (upper fibers of the Trapezius muscle) after performing manual visceral techniques on the diaphragm and some gastrointestinal areas. The hypothesis is that visceral manual maneuvers should have influence on craneofacial pain by modulating the autonomic nervous system

Interventions

Manual therapy applied by expert physiotherapist with minimum 15 years experience. Maneuvers aiming to improve the functional status of the diaphragm and gastrointestinal areas will be applied. These maneuvers pretend to mobilize and stretch the diaphragm and gastrointestinal areas, as well as relax them by means of pressure. Maneuvers are controlled, soft and painless. Subjects will remain lying down, lying side and seated. Intervention is applied once during 10 minutes in neuroscience laborat

Manual therapy applied by expert physiotherapist with minimum 15 years experience. Maneuvers aiming to improve the functional status of the diaphragm and gastrointestinal areas will be applied. These maneuvers pretend to mobilize and stretch the diaphragm and gastrointestinal areas, as well as relax them by means of pressure. Maneuvers are controlled, soft and painless. Subjects will remain lying down, lying side and seated. Intervention is applied once during 10 minutes in neuroscience laboratory of the Balearic Island University Interventors will use a cronometer and a list of the maneuvers to apply a repeatable methodology

Sponsors

University institute for research in health sciences (IUNICS)
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Functional gastrointestinal disorders according Rome IV elegibility criteria. Chronic migraine

Exclusion criteria

Cervical surgery Malformations of the cranio-cervical region Recent fractures or trauma to the cranio-cervical region Recent tumors and / or metastases. Pregnancy Bowel disease with risk of perforation: Chron, diverticulitis or gastroduodenal ulcer Gastric surgery Degenerative neurological diseases Psychiatric illnesses Hipertensive patients Manual treatment in the last week Intake of AINES, Triptans (asociated to acute episode of migraine) or Botolinum toxium last 24 hours Intake of chronic beta blockers

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026