None listed
Conditions
Brief summary
Pediatric Intensive Care (PICU) mortality in Sweden is low when compared internationally. At the same time, the prevalence of chronic complex illnesses among children treated in PICU has increased. It has been hypothesized that this is a contributing factor towards a change worldwide of deaths occurring later, after PICU discharge. Longer follow-up periods are therefore required to evaluate mortality related to PICU treatment. A cohort of patients treated in the PICU at Astrid Lindgren Children’s Hospital between 2008-2016 has been collected, providing survival data for at least four but up to twelve years. The main objective is to evaluate PICU and long-term mortality for different age and risk stratification groups using prospectively collected data archived in a Patient Data Management System (PDMS) and a national population register. Specifically, we aim to: 1. Study the association between severity of illness scores at admission and survival after PICU discharge for different age and diagnostic groups. 2. Compare the cohort with the background natural mortality, by a comparison of vital data for all children living in Sweden of the same age.
Interventions
A cohort of n=6520 admissions treated in the PICU at Astrid Lindgren Children’s Hospital, Karolinska University Hospital between 2008-2016 will be studied, providing survival data for at least four but up to twelve years. The main objective is to evaluate PICU and long-term mortality for different age and risk stratification groups using prospectively collected data archived in a Patient Data Management System (PDMS) and a national population register.
Data on survival status after PICU disch
A cohort of n=6520 admissions treated in the PICU at Astrid Lindgren Children’s Hospital, Karolinska University Hospital between 2008-2016 will be studied, providing survival data for at least four but up to twelve years. The main objective is to evaluate PICU and long-term mortality for different age and risk stratification groups using prospectively collected data archived in a Patient Data Management System (PDMS) and a national population register. Data on survival status after PICU discharge is obtained from the population register (Swedish Tax Agency), a separate national database. The duration of follow-up will be determined by the date when we collect data on survival (dead or alive) from the population register. Archived data will be accessed retrospectively with no active involvement by participants required.
Sponsors
Karolinska University Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Healthy volunteers
Yes
Inclusion criteria
Consecutive admissions between 2008-2016 of critically ill children to the PICU of a tertiary university hospital. Inclusion criteria for the control group was Swedish citizenship.
Exclusion criteria
Missing information on Predicted Death Rate (PDR) at admission. Missing Swedish Social Security Number Protected Identity
Outcome results
None listed