None listed
Conditions
Brief summary
This is a randomised controlled study of women who require an induction of labour, to determine if excess, or inappropriate infusions of fluid given via a vein (intravenous route) is having an effect upon the duration of labour. For this study, women who require an induction of labour will be randomised to receive intravenous fluid at a rate of 40 ml/hr or 250 ml/hr. The duration of labour (in minutes), will be calculated from the commencement of an intravenous infusion of a medication to start labour (a hormone called oxytocin), until the birth of the baby.
Interventions
Arm 1. Women requiring an induction of labour with oxytocin will be randomised to a background infusion of Hartmann's Compound Sodium Lactate (CSL) at 40 ml/hr. The background infusion of Hartmann's CSL will commence at the time of induction of labour, which is defined as the commencement of a separate intravenous infusion of oxytocin. The midwife caring for this patient will be responsible for the commencement of the intravenous line of oxytocin, as well as commencement of the intravenous line of Hartmann's CSL. The background infusion of Hartmann's CSL will cease, at the same time that the intravenous infusion of oxytocin ceases, which is post delivery of the placenta. The third stage of labour will be actively managed by controlled cord traction of the placenta and IM injection of 10 IU of oxytocin into the thigh of the woman. The background infusion of Hartmann's is a continuous infusion, the rate of which is not varied throughout labour. No intravenous fluid boluses of Hartmann's CSL or any other crystalloid is allowed for this study. The appropriate rate of the background infusion of Hartmann's CSL will be verified by an audit of the patient's fluid chart.
Sponsors
Study design
Eligibility
Inclusion criteria
Pregnant women of 37 weeks or greater gestational age, with a single pregnancy in a cephalic presentation who require an induction of labour
Exclusion criteria
Age < than 18 years Inability to consent Augmentation of labour, rather than induction of labour Pre-eclampsia Previous caesarean section Multiple pregnancy