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The influence of education on pain responses to acute exercise in people with knee osteoarthritis

The influence of education on pain responses to acute exercise in people with knee osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12621001266853
Enrollment
10
Registered
2021-09-20
Start date
2021-10-05
Completion date
2022-03-31
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Pain is multifactorial and involves both biological and psychological components. Multi-disciplinary treatment approaches incorporating drugs, cognitive-behavioural therapy and exercise interventions are the most efficacious for managing chronic pain. Single sessions of exercise and pain education are both demonstrated to have positive effects on pain in people with chronic pain such as osteoarthritis, however it is not known whether pain education delivered immediately prior to exercise can enhance the efficacy of exercise in relieving pain. Recent studies from our group have identified that the pain relieving effects of exercise involve a psychological component that influences the appraisal of pain; this would likely be augmented by a combination of exercise and education. The current project will examine the effect of explicit pain education about the pain relieving effect of exercise, compared to more general exercise and pain education, on pain responses to exercise in people with chronic osteoarthritis). The results will provide insight into the impact of pain education on the pain response to exercise and may have implications for how exercise and pain education are combined in clinical practice in the management of chronic pain

Interventions

The intervention will involve explicit education about the pain-relieving effects of exercise. The education will be delivered face to face (Group A) or online (Group B) via videoconferencing software by an Accredited Exercise Physiologist on an individual basis but will not be personalised for each participant. The intervention education component of the experiment will last approximately 15 minutes including content covering the pain-relieving effects of exercise such as exercise-induced hypoa

The intervention will involve explicit education about the pain-relieving effects of exercise. The education will be delivered face to face (Group A) or online (Group B) via videoconferencing software by an Accredited Exercise Physiologist on an individual basis but will not be personalised for each participant. The intervention education component of the experiment will last approximately 15 minutes including content covering the pain-relieving effects of exercise such as exercise-induced hypoalgesia (EIH) and the benefits of exercise for knee OA. The education will be delivered using pictures and analogies. The entire experimental session will last approximately 60 - 90 minutes, with the rest of the experimental session to consist of participants completing questionnaires relating to their health and level of physical activity (20 min), a bout of exercise (Group A: 20 min of moderate-intensity aerobic exercise at 60% of heart rate reserve performed on a stationary cycle ergometer (Monark 828e, Vansbro, Sweden)); (Group B: 20 min of home-based strengthening exercise at moderate intensity (e.g. rating of perceived exertion of 14/15 on Borg's 6-20 scale)) and pain assessments before and after exercise including pressure pain threshold testing for Group A (10min) and clinical pain ratings using a numeric pain rating scale for Group A and B (5min). All testing for Group A will be performed at the University of New South Wales and all testing for Group B will be conducted online via telehealth.

Sponsors

The University of New South Wales
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• You are aged 18 years or older and are able to speak, read and write English • You have a diagnosis of osteoarthritis in one or both knees and no other leg injuries/disabilities or surgeries • It is medically suitable for you to perform moderate intensity exercise

Exclusion criteria

• Any other type of arthritis apart from osteoarthritis of the knee or another cause of chronic pain other than knee osteoarthritis • You have been diagnosed with a serious psychiatric illness (e.g. major depression or severe anxiety) • You have been diagnosed with a serious cardiovascular, cardiopulmonary or neurological disease • Unable to refrain from pain medication for 24 h prior to the study • Unable to perform 20 minutes of moderate intensity exercise

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026