None listed
Conditions
Brief summary
This is a prospective randomized controlled trial comparing the outcome of patients undergoing primary total knee arthroplasty with either a midline or a lateral skin incision. Patient outcomes will be collected and compared between the two surgical cohorts over a 24 month post-operative period, and will include a range of subjective and functional outcomes, and kneeling tolerance. It is hypothesised that there will be no difference in kneeling tolerance between midline or lateral skin incisions.
Interventions
Patients will be randomised to receive either a midline skin incision or a lateral skin incision. All patients will undergo total knee arthroplasty via a medial parapatellar approach. Total knee arthroplasty will take from 60 to 90 minutes, surgical duration, across all groups. Within the group of treating surgeons there will also be a distribution of patients receiving a total knee arthroplasty via navigated and non-navigated techniques, and receiving cruciate retaining or cruciate sacrificing knee replacements as per the surgeons’ preferred practice. These will not be specifically controlled for in the randomisation process as they are unlikely to affect kneeling tolerance and doing so will limit the external validity of the trial. Randomisation will be stratified based on patella resurfacing or no patella resurfacing, as this may impact kneeling tolerance. Adherence to the randomisation schedule will be monitored by audit of the operation notes. Post-operatively, all participants will undergo routine rehabilitation for total knee arthroplasty, involving full weight bearing and early active range of movement. Post-operative analgesia will consist of paracetamol and non-steroidal anti-inflammatories, with opioids for breakthrough pain as per routine clinical treatment.
Sponsors
Study design
Eligibility
Inclusion criteria
- Age > 18 years - Primary TKA (including bilateral) - Undergoing a medial arthrotomy - Not currently being treated for a psychiatric disorder, senile dementia, Alzheimer’s disease, presence of alcohol/substance abuse.
Exclusion criteria
- Revision TKA (i.e. not primary surgery) - Existing contralateral TKA with <110 degrees of flexion movement - Poorly controlled diabetes or peripheral vascular disease - Range of motion of 90 degrees or less pre-operatively - Peripheral neuropathy or previous history of major spinal surgery - Previous medial incision around the knee joint longer than 5 cm - Previous major knee surgery (e.g. tibial tubercle transfer, tibial plateau fracture or open meniscus resection etc.)