Feasibility and Participant acceptability of use of the UriSWAB™ collection system

We will recruit 20 current smokers and/or e-cigarette users and/or people using nicotine replacement therapy that attend smoking cessation clinics, outpatient clinics or in-patient wards. Potential participants will be asked if they are interested to participate in the observational study, in person whilst in clinic. The clinicians in clinic will identify smokers or those using nicotine replacement therapy or eCigs based on clinical assessment (standard of care). Each potential participant will be offered a patient information sheet and consent form telling them about the study. They will have an opportunity to accept invitation on the day, or next time they present to clinic. Relevant demographic data will be recorded. Medical History, smoking variables and current medications will also be recorded. Patient demographic and clinical data will be collected from patients electronic or paper based medical records using a structured data collection form, the case report form (CRF). On the day of clinic (in either an outpatient or inpatient setting) an exhaled Carbon Monoxide reading will be collected (standard of care), and the ppt will be asked to provide a urine sample in a standard urine sample container and a UriSWAB™ sample. This collection of samples will be collected contemporaneously.