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Collaborative and Proactive Solutions for irritability in children and adolescents

Can a psychological intervention reduce irritability in children and adolescents more than usual care? A randomised-controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12621001027808
Enrollment
5
Registered
2021-08-05
Start date
2021-10-19
Completion date
2023-08-16
Last updated
2022-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Irritability is a highly prevalent, transdiagnostic symptom present in many commonly diagnosed child mental health disorders that confers risk for future anxiety, depression, and suicidality. Approximately 30-50% of children referred to mental health services experience severe irritability and irritable children place a high burden on the healthcare system with up to 15 times more service usage than children with mental health problems who are not experiencing irritability. There are currently no evidence-based treatments available that effectively reduce irritability and associated impairments. We will conduct a randomised controlled trial to test the efficacy of a psychological intervention, Collaborative and Proactive Solutions, for irritability in children and adolescents aged 5-15 years compared with usual care in terms of reducing irritability, and improving broader child and family wellbeing. Children referred to outpatient and community mental health services will be assessed for clinically significant irritability. Eligible children will be randomised to the CPS intervention (n=80) (8 sessions over 10 weeks) or usual clinical care from the mental health service (n=80). All participants will be assessed 4 and 12 months post-randomisation.

Interventions

The intervention is a psychological therapy called Collaborative & Proactive Solutions. It will be delivered by study trained clinicians. The intervention comprises 8x1 hour sessions once a week for six weeks and then once every two weeks for the final 2 sessions (total of 8 sessions over 10 weeks). The intervention is administered face-to-face, or via telehealth, with the child and parent/s. Sessions can include time with the parent/s alone, with the child alone, and with both the child and par

The intervention is a psychological therapy called Collaborative & Proactive Solutions. It will be delivered by study trained clinicians. The intervention comprises 8x1 hour sessions once a week for six weeks and then once every two weeks for the final 2 sessions (total of 8 sessions over 10 weeks). The intervention is administered face-to-face, or via telehealth, with the child and parent/s. Sessions can include time with the parent/s alone, with the child alone, and with both the child and parent/s present. The structure of the intervention is as follows: (a) Identification of lagging skills and unsolved problems that contribute to temper outbursts, and a discussion of how existing parental responses may be counterproductive; (b) Prioritization—helping parents prioritize which unsolved problems will be the focal point of initial problem-solving discussions; (c) Introduction of the Plans framework— helping parents understand the three potential responses to solving problems: Plan A (solving a problem unilaterally, through imposition of adult will and often accompanied by adult-imposed consequences), Plan B (solving a problem collaboratively and proactively), and Plan C (setting aside the problem for now); and (d) Implementing Plan B—helping parents and children become proficient in the use of Plan B and largely discontinuing the use of Plan A. Although the clinician actively guides the problem-solving process initially, the goal of treatment is to help the child and parents become increasingly independent in solving problems together. Clinicians will complete a Clinical Record Form (CRF) for each session to document adherence to intervention protocols.

Sponsors

Melissa Mulraney
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
5 Years to 15 Years
Healthy volunteers
No

Inclusion criteria

Children aged 5-15 years with a score of 3 or higher on the parent rated Affective Reactivity Index.

Exclusion criteria

- Major illness or disability (e.g., intellectual disability) - Non-English speaking - Children with a psychotic disorder (e.g. schizophrenia or bipolar disorder), at risk of self-harm will be excluded from the study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026