Yield of same day dual endoscopy for patients referred for assessment of positive Fecal Occult Blood Test.

Effect of same day dual endoscopy on frequency of common gastrointestinal conditions and gastrointestinal symptoms for patients referred for assessment of positive Fecal Occult Blood Test.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12621000984897

Enrollment

783

Registered

2021-07-27

Start date

2019-10-21

Completion date

2021-01-20

Last updated

2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will investigate the effect of same day dual endoscopy on finding common gastrointestinal conditions for patients referred for assessment of positive Fecal Occult Blood Test (Bowel cancer screening test) Who is it for? You may be eligible to join this study if you are aged 50 and above, and have been referred for investigation of positive Fecal Occult Blood Test (Bowel cancer screening test) Study details: All participants in this study will have two endoscopy procedures on the same day: an upper (gastroscopy) and lower (colonoscopy) as part of the routine clinical care for patients with a positive fecal occult blood test. We would also access your electronic medical records so we can confirm your diagnosis and test results. The findings from both upper and lower endoscopy will be used to evaluate occult GI bleeding. Participants will not be asked to attend any additional appointments, outside their scheduled clinical visits. This study therefore has no effect and no foreseeable risk of harm to its participants. No attempts at directly contacting the patient or their family will be made. All the relevant findings from the endoscopy (both gastroscopy and colonoscopy) will be discussed with the participants by their gastroenterologist. It is hoped these findings will provide further guidance/evidence to support the routine use of both upper and lower endoscopy for the evaluation of occult GI bleeding.

Interventions

This study has a prospective and a retrospective component. This study is single center study, which will be conducted at the Gastroenterology department at the Princess Alexandra hospital. For the retrospective component, we will audit all patient records who have undergone Gastroscopy and Colonoscopy on the same day for investigation of positive FOBT from Jan 2010 until July 2019. Gastroscopy which will take approximately 10 mins will be done on the same day as the colonoscopy (either immediately before or after the colonoscopy). There will be no additional anesthesia or observation required for the gastroscopy. Both colonoscopy and gastroscopy will be performed by a gastroenterologist. Patients will not be required to fill additional questionnaire or have phone interviews. The retrospective part of the study will involve reviewing electronic medical records to collect information (demographic details including age, sex, BMI, ethnicity, medications, co-morbidities, outcomes of gastroscopy and colonoscopy, quality of bowel preparation, laboratory data (Full blood count, celiac serology, Iron studies and Helicobacter pylori status)) for patients who have undergone same day gastroscopy and colonoscopy. The participants would have undergone this screening procedure in the absence of this study

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

All patients referred for investigation of positive FOBT will be considered for participation in study.

Exclusion criteria

None

Outcome results