None listed
Conditions
Brief summary
The aim of this project is to compare the effectiveness and individual experience of supervised and structured aerobic exercise to resistance exercise on key clinical outcomes in people with Systemic Lupus Erythematosus.
Interventions
The two treatment groups being compared in this trial is an aerobic exercise program to a strength exercise program. Both exercise programs will be individually prescribed and tailored to the participants' rating of perceived exertion, by the principal investigator who is an Accredited Exercise Physiologist.
Both exercise programs will be performed at the Australian Catholic University, North Sydney gymnasium and supervised by a team of Exercise Scientists and Exercise Physiologists who have be
The two treatment groups being compared in this trial is an aerobic exercise program to a strength exercise program. Both exercise programs will be individually prescribed and tailored to the participants' rating of perceived exertion, by the principal investigator who is an Accredited Exercise Physiologist. Both exercise programs will be performed at the Australian Catholic University, North Sydney gymnasium and supervised by a team of Exercise Scientists and Exercise Physiologists who have been trained by the principle investigator in the delivery of the exercise programs. Both exercise programs will be dose matched, with all participants performing their allocated exercise program in the gymnasium two times per week, 50-minutes in durations, and at moderate intensity [3 to 4 out of 10 based on your rating of perceived exertion (RPE), which is referred to as “somewhat hard”]. All exercise sessions will include a 10-minute warm-up (5-minutes walking on a treadmill and 5-minutes of body weight exercises replicable to the session), 32 minutes of their allocated type of exercise at moderate intensity exercise, and an 8-minute cool down which will include whole body stretches and breathing. The aerobic exercise program will involve walking on a treadmill for 32 minutes, performing 4-minute moderate intensity intervals subsequent to 4-minute low intensity intervals [2 to 3 out of 10 based on your RPE, which is referred to as “light”]. Heart rate (HR) and RPE will be monitored throughout the 32-minute duration to ensure the participant is working within the desired RPE and HR intensities, and if they are reporting an RPE that is either too low or too high, adjustments may be made to the speed or incline of the treadmill. The strength exercise program will involve a circuit of 8 whole body exercises performed at a dosage of 10 repetitions and 3 sets of each exercise. These exercises will be using mostly body weight for resistance, as well as the use of props such as TheraBand's, dumbbells, and kettle bells. RPE will be closely monitored during the 32-minute duration to ensure that the participant is working at the desired intensity, and if they are reporting an RPE that is either too low or too high, adjustments may be made to the exercises (for example, less or more resistance to the exercise). Each participants' exercise program, regardless of exercise type, will be individualised based on their RPE. For example, for the aerobic exercise program, one participant may be walking on the treadmill at a speed of 5km/hour, where another participant may be walking on the treadmill at a speed of 4km/hour. For example, for the resistance exercise program, one participant may be performing a sit-to-stand exercise using their own body weight, and another participant might require an additional dumbbell for added resistance.
Sponsors
University of Southern Queensland
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adults (18+) Diagnosis of systemic lupus erythematosus by the classification criteria ACR and the 2019 EULAR Classification Criteria for systemic lupus erythematosus. Complete a self-created screening questionnaire by the principle investigator, as well as the Exercise & Sports Science Australia (ESSA) adult-pre-screening tool and be stratified as low-moderate risk. If they are deemed to be moderate-high risk, more information may need to be sought from their regular treating physician to determine their eligibility for inclusion. The principal investigator, Stephanie Frade, who is an Accredited Exercise Physiologist will be completing the screening with all participants over the phone, and will deem whether they are eligible and safe to complete the exercise program.
Exclusion criteria
• Currently pregnant. This will be informed by a self-created screening tool that will be completed by the principle investigator over the phone prior to commencing their baseline assessment. • Absolute contraindications including: Active lupus nephritis, myocarditis, or pericarditis. This will be informed by a self-created screening tool that will be completed by the principle investigator over the phone prior to commencing their baseline assessment. • Relative contraindications. This will be informed by a self-created screening tool and Exercise & Sports Science Australia screening tool that will be completed by the principle investigator over the phone prior to commencing their baseline assessment.
Outcome results
None listed