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A clinical audit of opioid reduction in patients undergoing treatment with medicinal cannabis for chronic non-cancer pain

A clinical audit of opioid reduction in patients undergoing treatment with medicinal cannabis for chronic non-cancer pain

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12621000875808
Enrollment
155
Registered
2021-07-06
Start date
2020-11-02
Completion date
2022-10-31
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients referred to the chief investigator’s chronic pain management clinic where appropriate are treated with medicinal cannabis. Many of these patients are already taking opioid drugs (morphine-like drugs), which seldom control their pain and in many cases are deleterious to their health. This study will evaluate outcomes in a group taking both opioids and cannabinoids in comparison to a group taking opioids but not taking cannabinoids.

Interventions

Patients referred to Dr Finch's chronic pain management clinic for treatment of non-cancer pain where appropriate are treated with medicinal cannabis. Many of these patients are already taking opioid drugs (morphine-like drugs), which seldom control their pain and in many cases are deleterious to their health. This study will evaluate outcomes in a group taking both opioids and cannabinoids in comparison to a group taking opioids but not taking cannabinoids at 6-month intervals for up to 2

Patients referred to Dr Finch's chronic pain management clinic for treatment of non-cancer pain where appropriate are treated with medicinal cannabis. Many of these patients are already taking opioid drugs (morphine-like drugs), which seldom control their pain and in many cases are deleterious to their health. This study will evaluate outcomes in a group taking both opioids and cannabinoids in comparison to a group taking opioids but not taking cannabinoids at 6-month intervals for up to 2 years post-enrolment. Assessments will include a pain diagram, the numerical pain rating score, Oswestry Disability Index (ODI), their insomnia severity (ISI) and their medication history, especially opioid consumption. The assessments take up to 20 minutes to complete. Participants will attend a face-to-face session to complete the questionnaires at the Perth Pain Management Centre, or via videoconference. Questionnaires will be administered in the waiting room before a consultation with a pain specialist, or will be completed via email before a telehealth consultation.

Sponsors

Dr Philip Finch
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Chronic non-cancer patients referred to Perth Pain Management Centre or to Dr Michael Kent who were taking opioid medications at or after the commencement of the audit (November 2020).

Exclusion criteria

Cannabinoid exclusion - previous significant drug addiction, pregnancy, lactation, previous psychotic illness, age (under 18) and relative exclusions of heart and liver disease.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026