None listed
Conditions
Brief summary
The purpose of this study is to determine whether high intensity interval training can improve health outcomes and influence the gut micro biome in breast, prostate and colorectal cancer survivors. Who is it for? You may be eligible for this study if you are an adult with confirmed breast, prostate or colorectal cancer, and are at least one month post-treatment completion for cancer. Study details: All participants will undertake an initial 4-week supervised training phase, with 3 sessions per week of exercise with an Accredited Exercise Physiologist or equivalent. Following the supervised phase, participants will enter a 6-month maintenance period where they will be asked to maintain 150 minutes of moderate intensity or 75 minutes of vigorous intensity or a combination, therefore meeting the Australian exercise oncology guidelines. It is hoped that this research will help determine if exercise, and especially high intensity exercise, is effective in positively influencing the gut microbiome and other health outcomes in cancer survivors.
Interventions
Controlled intervention will compare microbiome changes over six-months between cancer types. All participants will complete a four-week training program, supervised by an Accredited Exercise Physiologist or equivalent. This initial program will require attendance three times per week and entail a high-intensity interval training protocol of 4x4 minute intervals at 85-95% HRpeak, with three minute active recovery bouts between each interval. Attendance will be recorded in a supervised-training logbook. Similarly, adherence to 85-95% HRpeak during intervals will be recorded. This protocol requires a total of 38 minutes exercise and all exercise will be conducted on a cycle ergometer. The purpose of this period is to ensure all participants understand the exercise protocol and are able to complete it safely during the remainder of the study. Participants will then be provided with access to a facility with all required equipment available and encouraged to complete three sessions per week for the next six months. Participants will also be advised to maintain 150 minutes of moderate intensity or 75 minutes of vigorous intensity or a combination, therefore meeting the Australian exercise oncology guidelines. Participants will keep a log of the date and duration of exercise completed. Participants will be recruited from the Brisbane area, with the intervention being run from the University of Queensland and partnered gyms in the wider Brisbane area.
Sponsors
Study design
Eligibility
Inclusion criteria
-Histologically confirmed breast, prostate and colorectal cancer - Aged 18 years or older - At least one-month post-cancer treatments and not intending to undergo any further treatment during the study period - Free of any musculoskeletal, neurological, respiratory, metabolic or cardiovascular conditions that may prevent safe completion of the exercise demands of the study
Exclusion criteria
- Currently performing high intensity interval training more than four times per month - Unable to travel to the training/testing facilities - Unable to give informed consent - Participant is pregnant or becomes pregnant during the study period