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Tracking Outcomes Post Intensive Care

Tracking Outcomes Post Intensive Care (TOPIC): Incidence of Post intensive care syndrome among patients treated and discharged from Intensive Care Units

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12621000628842
Acronym
TOPIC
Enrollment
227
Registered
2021-05-26
Start date
2020-12-14
Completion date
2022-10-01
Last updated
2023-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Up to 80% of people discharged from the ICU experience various physical, cognitive, and/or psychological complications and enduring impairment, termed ‘post intensive care syndrome’ (PICS). The prevalence and burden of PICS remains uncertain, and current interventions are not effective longer-term; further research into prevention, early diagnosis and intervention of this syndrome is considered internationally is a priority. The interlinked aims of this study are 1. To describe the predictors, correlates and prevalence of PICS, and 2. To use this information to develop screening, diagnostic and outcome measures for use in research and clinical practice.

Interventions

Discharged from a participating ICU - Participants contacted via preferred method (telephone, email, post) at 6 weeks and 6 months post ICU discharge. - At both timepoints, participants complete validated self-reported measures for physical & cognitive function, as well as depression, anxiety and PTSD symptoms. - A retrospective electronic medical record audit is conducted for all participants that complete at least 6 week follow-up measures described above. - The medical record audit will coll

Discharged from a participating ICU - Participants contacted via preferred method (telephone, email, post) at 6 weeks and 6 months post ICU discharge. - At both timepoints, participants complete validated self-reported measures for physical & cognitive function, as well as depression, anxiety and PTSD symptoms. - A retrospective electronic medical record audit is conducted for all participants that complete at least 6 week follow-up measures described above. - The medical record audit will collect demographic information, presenting complaint, ICU length of stay, APACHE score, Charlston Comorbidity Index, results of delirium screening measures, as well as hospital codes for icu complications as well as readmissions between the date of discharge, and the date 6 month follow-up was due.

Sponsors

Dylan Flaws
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

People discharged from participating ICUs will be eligible to participate if they are: • Aged 18 years or over • Residing in Australia • Sufficiently fluent in English to complete recruitment and data collection processes (assessed at time of seeking permission to contact 6 weeks post discharge) • Provide consent to collection of data from their medical records AND at least partial data from questionnaires at 6 weeks post ICU discharge.

Exclusion criteria

• Patients whose life expectancy at discharge is estimated by their clinical team to be less than 12 months • Age <18 years • Unable or unwilling to provide consent to participate for the duration of the study • Provide consent, but do not provide data at 6 weeks post ICU discharge

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026