None listed
Conditions
Brief summary
This is a 12-week RCT to investigate three key metabolic markers in the weight loss context using two different dietary approaches: a conventional low fat approach (LF) and a carbohydrate restricted approach. The markers are: i. F2 prostanes, a marker of oxidative stress; ii. the ratio of omega 6 to omega 3 polyunsaturated fats, specifically arachinonic acid (AA) to eicosapentanoic acid (EPA); iii. , and iii. blood glucose patterning. Other outcomes will be body composition, weight, waist circumference, and visceral fat, The hypothesis is that the carbohydrate-restricted group will show a higher AA to EPA ratio, a reduced F2 isoprostane (oxidative) response and a more even blood sugar pattern compared to the low fat group.
Interventions
This randomised controlled trial (RCT) is a 12-week dietary intervention comparing a low carbohydrate, high fat (LCHF) way of eating with a control mainstream-nutrition-guided group in a group of navy personnel from the New Zealand Defence Force (NZDF). The LCHF diet is defined as <130g carbohydrates per day; 15-25% of total energy from protein; >60% of total energy from fat. Participants will be required to consume 3 meals a day (or the addition of more meals as long as it does not exceed their energy threshold) for 12 weeks. Participants will be expected to prepare their own food but will be provided with detailed instructions / resources / recipes to assist them. Resources provided to them will be a combination of those designed specifically for this research, and associated websites for recipes and other information (www.ditchthecarbs.com and www.dietdoctor.com). The dietitian and nutritionist will be administering the intervention. Participants will be required to track their dietary intake for a 2-week period at two time-frames (weeks 1-3, and weeks 6-8) on a free smart phone app called Easy Diet Diary. This will be sent to the research team who has access to the partner application, Foodworks for analysis. Research assistants that are nutrition-trained will be undertaking group sessions with participants every two weeks, where they will use food frequency questionnaires to measure adherence.
Sponsors
Study design
Eligibility
Inclusion criteria
Navy personnel that are over 125kg and are registered on the FIT for LIFE programme with the NZ Defence Force
Exclusion criteria
Less than 125 kg Not on the FIT FOR LIFE programme Pregnant or breastfeeding females