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Quality or Quantity: The Role of Carbohydrate in the Health of Children with Diabetes.

Quality or Quantity: The Role of Carbohydrate in the Health of Children with Diabetes.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12621000443897
Enrollment
65
Registered
2021-04-16
Start date
2021-08-05
Completion date
2023-02-22
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

There are an increasing number of families attending the Diabetes Clinic at Perth Children’s Hospital (PCH) who are using low carbohydrate (CHO) diets in an attempt to control blood glucose levels. However, little is known about what these children are eating and their overall nutritional status. The use of these diets is often promoted for weight loss in adults; however, there is minimal evidence on the short and long-term impacts on the use in children. As such, they are not promoted in clinical guidelines or in the clinical setting and families are seeking advice elsewhere such as non-evidence based online forums. This study aims to determine if children with T1D on low CHO diets are at greater risk of poor nutritional status, cardiovascular disease, osteoporosis and poor psychosocial functioning, compared to those who meet the daily recommended CHO targets for children. The findings will directly inform future studies and clinical practice to benefit children with T1D. All children aged 10 years and younger with T1D for more than 1 year will be invited to participate in the study. A population–based sample of 100 children will attend PCH on one occasion to measure: non-fasting bloods (to assess biomarkers for malnutrition, cardiovascular disease, kidney and liver function); height; weight; blood pressure; bone density and body composition (using dual energy X-ray absorptiometry (DXA)) and; questionnaires to assess physical activity and psychosocial functioning. Participating families will complete a 4-day food diary to assess dietary intake, which will be entered into a nutrient analysis program. Statistical analyses will determine associations between proportion of energy from CHO, types of CHO-containing foods, nutritional status and risk factors for co-morbidities.

Interventions

This is an observational quantitative cross sectional study assessing the association between carbohydrate (CHO) restriction and a multitude of health outcomes including nutritional status, cardiovascular disease, glycaemic control, bone density and psychosocial functioning in children 10 years and younger with Type 1 Diabetes (T1D) in Western Australia (WA). A population–based sample of 100 children will be invited on one occasion to measure: non-fasting bloods (to assess biomarkers for malnutr

This is an observational quantitative cross sectional study assessing the association between carbohydrate (CHO) restriction and a multitude of health outcomes including nutritional status, cardiovascular disease, glycaemic control, bone density and psychosocial functioning in children 10 years and younger with Type 1 Diabetes (T1D) in Western Australia (WA). A population–based sample of 100 children will be invited on one occasion to measure: non-fasting bloods (to assess biomarkers for malnutrition, cardiovascular disease, kidney and liver function); height; weight; blood pressure; bone density and body composition (using dual energy X-ray absorptiometry) and; study specific questionnaires to assess physical activity, psychosocial functioning and socio demographic background. The participants will be asked to complete each of the questionnaires and assessments described above during the initial visit. It is anticipated that the questionnaire will take no longer than 40 minutes to complete. The questionnaires will be conducted by research nurse or research dietitian. Participating families will complete a 4-day food diary to assess dietary intake.

Sponsors

Telethon Kids Institute
Lead SponsorOther Collaborative groups

Eligibility

Sex/Gender
All
Age
2 Years to 10 Years
Healthy volunteers
No

Inclusion criteria

1) Type 1 diabetes for at least 1 year 2) Aged between 2 and 10 years 3) Able to attend Perth Children’s Hospital for one visit

Exclusion criteria

The parent/caregiver is unable to read and complete questionnaires in English.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026