None listed
Conditions
Brief summary
ADAPT-MRL is a multi-site, multinational, observational cohort registry designed to collect data on the use of the MR-Linac machine for radiation therapy oncology and patient outcomes. The registry will provide a linked repository of technical and clinical data that will be shared with the device manufacturer. Who is it for? You may be eligible to be involved in this registry if you have cancer and are scheduled for treatment using an MR-Linac machine for radiation therapy. Study details Participants will be enrolled in the study, attend standard of care treatment and follow up visits at 3, 6, 9, 12, 18 and 24 months. Participants are asked to complete additional quality of life surveys at these visits and may choose to have additional scans performed. It is expected the registry will recruit patients for up to 10 years. This data will be used to leverage the MR-Linac’s capabilities and design new and improved treatment strategies. An estimated 10,000 patients will be enrolled to this registry across 10 or more study sites situated in Australia and internationally (additional sites to be added).
Interventions
Radiation therapy delivered using an MR-Linac by radiation oncologists and their associated team (physicist, radiation therapist etc.).
Treatment is delivered to patients individually in a clinic. The dose of radiation, the number of times and frequency of its delivery is prescribed for each individual patient based on their disease and health status. This prescription is determined by the radiation oncologist and treatment plans are verified by their colleagues. Patients are involved in comple
Radiation therapy delivered using an MR-Linac by radiation oncologists and their associated team (physicist, radiation therapist etc.). Treatment is delivered to patients individually in a clinic. The dose of radiation, the number of times and frequency of its delivery is prescribed for each individual patient based on their disease and health status. This prescription is determined by the radiation oncologist and treatment plans are verified by their colleagues. Patients are involved in completing patient reported outcomes measures and may choose to allow optional images to be taken. Data will be collected from the electronic medical record used at participating sites. Retrospective data will be collected for participants who enrolled in the study prior to relevant patient reported outcomes measures being available. The information collected and timepoints for these patients is identical to prospective patients except patient reported outcomes will not be available. This study will capture data on the treatments delivered using the MR-Linac machine.
Sponsors
GenesisCare Clinical CRO Pty Ltd
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Willing to provide written informed consent; 2. Participant must be 18 years or older, at the time of signing the informed consent; 3. Scheduled for treatment on an MR-Linac device or have completed treatment on an MR-Linac device.
Exclusion criteria
None
Outcome results
None listed