Comparing coronary microcirculatory resistance by magnetic resonance imaging to invasive measurement of microcirculatory resistance

Magnetic resonance Imaging-based Coronary Resistance index cOmpared to the invasive index of microcirculatory resistance in patients with non-obstructive coronary artery disease

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12621000270819

Acronym

MICRO

Enrollment

Registered

2021-03-11

Start date

2022-03-18

Completion date

2023-03-17

Last updated

2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients with non-obstructive coronary artery disease, who have had a comprehensive invasive coronary physiology assessment, will be asked to undergo a research cardiac MRI within two weeks of their invasive assessment. The results of the MRI will be compared to the invasive assessment. This will provide information on the utility of the new MRI method for diagnosis of coronary microvascular dysfunction.

Interventions

Patients with non-obstructive coronary artery disease on invasive coronary angiography will undergo a cardiovascular MRI scan 2 weeks after angiography to measure coronary microvascular resistance. The comprehensive MRI scan will take approximately 2 hours. There is no follow-up for this study.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients with non-obstructive coronary artery disease who have had comprehensive invasive coronary physiology assessment with no evidence of microvascular disease

Exclusion criteria

Obstructive coronary artery disease Haemodynamic instability from cardiogenic shock Severe asthma Heavily calcified or tortuous vessels Inability to provide informed consent

Outcome results