None listed
Conditions
Brief summary
Heart and/or lung transplantation is performed in patients with significant co-morbidities and burden of disease. Their peri-operative period is high risk and recovery may be prolonged due to the risk of complications. There is considerable effort applied to appropriate risk stratification and selection of these patients prior to listing for transplantation. Recently sarcopenia has been used as a surrogate for frailty. Patients undergoing heart and/or lung transplant surgery may be particularly susceptible to the risks associated with frailty. In heart/lung transplant surgical patients objective measurements of sarcopenia has been difficult and not fully investigated. The hypothesis of this study is that reduced cross sectional area of the rectus femoris muscles as assessed by ultrasound and/or reduced heart rate variability will be associated with poorer outcomes amongst cardio-thoracic patients undergoing major surgery.
Interventions
The rectus femoris muscle will be measured using ultrasound. This will occur in the outpatient clinic prior to surgery. The ultrasound takes less than 5 minutes and will be performed by an anaesthetist who is part of the research team. A 5 minute electrocardiograph (ECG) recording will also be performed for subsequent analysis
Sponsors
St Vincent’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All patients undergoing heart and/or lung transplantation
Exclusion criteria
None
Outcome results
None listed