None listed
Conditions
Brief summary
On FOUR separate occasions, the subjects will consume randomly assigned beverage (within 5 min) containing one of the FOUR test products. In total two intervention products and two competitor products will be testec, each one week apart. Dairy UHT beverage containing 10% -14% protein will be compared to competitor UHT products containing 10% - 14% protein effect on postprandial amino acid absorption, paracetamol absorption, blood glucose and insulin response.
Interventions
Subjects will arrive at the provider’s laboratory, after an overnight fast. Following insertion of an intravenous catheter, an initial blood sample will be taken into heparin-treated BD Vacutainers as well as gold top vacutainers for serum. Prior to consumption, 1000 mg paracetamol will be added to all of four beverages to be consumed ( in randomised order) and the beverage thoroughly mixed. The subjects will then consume the assigned beverage (within 5 min) in front of the research technician
Subjects will arrive at the provider’s laboratory, after an overnight fast. Following insertion of an intravenous catheter, an initial blood sample will be taken into heparin-treated BD Vacutainers as well as gold top vacutainers for serum. Prior to consumption, 1000 mg paracetamol will be added to all of four beverages to be consumed ( in randomised order) and the beverage thoroughly mixed. The subjects will then consume the assigned beverage (within 5 min) in front of the research technician. Seven further blood samples will be taken over 4 hours at times +15, +30, +60, +90, +120, +180, and +240 following baseline. Samples will be separated by centrifugation for 15 minutes (within 15 minutes of collection). Serum and plasma will be aliquoted and stored at -80 degrees till analysed. Participants present on four separate occasions in total and two intervention products and two competitor products will be tested, each one week apart. Beverages include: Dairy milk UHT beverage containing 10% protein, Dairy milk UHT beverage containing 10% protein, competitor Dairy milk UHT containing 10% protein, competitor Dairy milk UHT containing 14% protein.
Sponsors
Massey University, Palmerston North
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
BMI below 35; Non-smoker;
Exclusion criteria
Diagnosed with cancer, vascular disease or diabetes; having any GIT diseases; kidney or liver impairment; recent major surgery and sensitive to dairy products; vegetarian; sensitive to paracetamol; taking anticoagulants; exceeding moderate alcohol intake; endocrine disease; allergic to plasters.
Outcome results
None listed