None listed
Conditions
Brief summary
Secondary intention healing, also known as laissez-faire, was first described in eyelid surgery in 1957. However, it is more common for surgical reconstruction to occur after skin lesion excision from the eyelids. There have been a few case series, advocating laissez-faire as a viable alternative treatment option with promising results that is not inferior to surgical reconstruction. The objective of this randomised control trial is to randomly assign cases that have had lower lid lesions removed to either Laissez-faire or surgical wound closure, and analyse the outcomes. We predict that there is no difference in outcome or at least no inferiority between Laissez-faire compared to primary direct closure.
Interventions
After excision of lower lid lesions, cases that can be repaired by a direct closure technique will be randomised to direct closure with suturing of the wound ( the standard treatment)by one of the ophthalmologists in the research team in an operating theatre, or laissez-faire ( left to heal by secondary intention). This is the intervention, and only occurs once. This will be carried out in an ophthalmology clinic. The patient not have any sutures inserted in to the eyelid defect. No dressin
After excision of lower lid lesions, cases that can be repaired by a direct closure technique will be randomised to direct closure with suturing of the wound ( the standard treatment)by one of the ophthalmologists in the research team in an operating theatre, or laissez-faire ( left to heal by secondary intention). This is the intervention, and only occurs once. This will be carried out in an ophthalmology clinic. The patient not have any sutures inserted in to the eyelid defect. No dressing will be applied. The patient will be given instructions on self care of the wound - by performing wound care to clean the eyelid as necessary with supplied materials & saline solutions. The patient will apply antibiotic ointment to the wound for several days. All patients will be seen & assessed again within 4-5 days of their initial tumour excision. Any additional interventions that are required will be recorded by one of the investigators at the post-operative visits.
Sponsors
Dr Stephen Ng
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients undergoing excision of lower lid lesions that result in defects that are able to be closed by a direct closure technique.
Exclusion criteria
Age less than 20 Patients who decline to give consent Patients unable to give consent
Outcome results
None listed