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Morbidity Post COVID-19 - Investigation and call to action

Morbidity Post COVID-19 - Investigation and call to action

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620001114932
Enrollment
200
Registered
2020-10-28
Start date
2020-11-02
Completion date
2021-01-29
Last updated
2020-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this project is to document over a period of a six-month period the post morbidity problems including pulmonary, functional, neurocognitive and health related quality of life for those patients infected with COVID-19. Results will be compared between severity levels of the infection (mild, severe and critical) and adjusted for the premorbid age adjusted Charleson Comorbidity Score. It is hypothesised those subjects with a positive diagnosis of COVID -19 will have abnormal results when compared to population norms in pulmonary function, functional ability, neurocognitive status and health related quality of life.

Interventions

This research will conduct observational measures to detect impairments that may be present as a direct result of COVID-19 infection. Participants involved will have had a positive COVID-19 test along with a hospital admission to an actual ward or virtual ward. Participants involved will also have recovered from coronavirus infection and will now no longer have a positive coronavirus test. Participants will attend the Physiotherapy and Thoracic Medicine Departments for a total of 4 visits over a

This research will conduct observational measures to detect impairments that may be present as a direct result of COVID-19 infection. Participants involved will have had a positive COVID-19 test along with a hospital admission to an actual ward or virtual ward. Participants involved will also have recovered from coronavirus infection and will now no longer have a positive coronavirus test. Participants will attend the Physiotherapy and Thoracic Medicine Departments for a total of 4 visits over a 6-month period (Every 2 months post initial visit on recruitment). Each participant will be required for a total of 1-hour for each visit, total of 4 hours over a 6-month period. During the visit the participants will undergo the following observational tests: - Respiratory Function Testing (Spirometry) - 15 minutes - 6 Minute Walk Test (Physical fitness) - 8 minutes - Ultrasound of rectus femoris muscle (Muscle cross sectional area) - 5 minutes - FIM (Physical function) - 5 minutes - Short Form-36 Questionnaire (Quality of Life) - 5 minutes - The Zung Self-rated Anxiety Scale (Anxiety) - 5 Minutes - The Zung Self-rated Depression Scale (Depression) 5 minutes - Montreal Cognitive Assessment (Cognitive Function) 10 minutes

Sponsors

The Royal Brisbane and Women's Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Inclusion criteria will be all patients who tested positive for COVID-19, greater than 18 years and who were monitored or admitted to Metro North during 2020. This includes patients admitted to intensive care, the COVID-19 wards at RBWH and those patients in the Metro North “Virtual Ward”.

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026