Skip to content

An Intervention to improve Primary Care Adherence To Heart Failure guidelines IN Diagnosis, Evaluation & Routine management (PATHFINDER) pilot program

An Intervention to improve Primary Care Adherence To Heart Failure guidelines IN Diagnosis, Evaluation & Routine management (PATHFINDER) pilot program

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12620001069943
Acronym
PATHFINDER (Primary Care Adherence To Heart Failure guidelines IN Diagnosis, Evaluation & Routine ma
Enrollment
6
Registered
2020-10-19
Start date
2021-01-28
Completion date
2023-09-01
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The project's aim is to conduct a pilot randomised controlled trial to determine the efficacy of PATHFINDER on outcomes for heart failure with reduce ejection fraction over a 6-month period. Two hundred patients with CHF will be randomised to receive the PATHFINDER Heart Health Plan or control (usual care). For the PATHFINDER group, the project’s Nurse Practitioner (NP) will help facilitate the transition from tertiary to primary care including a Heart Health Plan, and be a point of contact for GPs needing support for medication titration. Referrals for cardiac rehabilitation program or exercise training program will be facilitated by the NP, with input from other Allied Health Professionals. Complex issues will be triaged for cardiologist support through the Advanced Heart Failure and Cardiac Transplant Service (FSH) . Primary outcome includes proportion of patients adhering to guideline-recommended treatment at 6 months post-enrolment. Secondary outcomes include proportion of patients receiving the guideline-recommended treatment independently at 6 months post-enrolment; exercise training program or cardiac rehabilitation program adherence by 6 month post-enrolment, 6 minute walk test distance, patient-reported outcome includes Kansas City Cardiomyopathy Questionnaire-short version (KCQ12), Patient Health Questionnaire (PHQ-2),Medication Compliance Questionnaire at baseline following enrolment and 6 month post-enrolment, ;PROMIS Physical Function Short Form 4a, Self-care of Heart Failure Index at 6 months post-enrolment.

Interventions

a) Physical or informational materials used: There are two distinct components to the PATHFINDER intervention, i.e. the information/resources provided to the patients and the medication titration plan etc. for GPs. Heart failure (HF) education materials will be given to patients to support self-management ;PATHFINDER study follow up forms (including assessment, medication titration plan, HF helpline, problem solving guide) will be provided to patients’ GPs to support titrating medication to targ

a) Physical or informational materials used: There are two distinct components to the PATHFINDER intervention, i.e. the information/resources provided to the patients and the medication titration plan etc. for GPs. Heart failure (HF) education materials will be given to patients to support self-management ;PATHFINDER study follow up forms (including assessment, medication titration plan, HF helpline, problem solving guide) will be provided to patients’ GPs to support titrating medication to target dose. b) each of the procedures, activities, and/or processes used: HF education to patients upon discharge; patients be referred to cardiac rehabilitation program (an existing program in care system, involving a health care team, a personalised education and exercise program, the program runs 30-50 minute per session, two to three times per week and for 6-10 weeks depending on patients' health condition) ; medication titration support for GP post-discharge with cardiologist support through the Advanced Heart Failure and Cardiac Transplant Service (FSH); The type of support for GPs will be medication titration plan at discharge; HF helpline, unlimited phone calls or video-conferencing for case management. The NP will review the case initially and provide recommendations that are within their scope of practice. For more complex cases and those that are outside their scope of practice they will escalate the case to a cardiologist who will review and provide recommendations. c) who will deliver the intervention: the study HF nurse practitioner (NP) will deliver the heart failure education after enrolment , facilitated cardiac rehabilitation program, and PATHFINDER study follow up forms; HF NP will triage and facilitate medication titration support. GPs will receive the PAHTFINDER study follow up form when patients visit GPs. If the GP needs support, they will contact HF helpline (HF NP )in the first instance, who will either provide advice or escalate to a cardiologist as described at b). (NP helpline has been created specifically for GPs for this study. The aim of NP helpline is to help GPs to manage patients' HF symptoms and patients' heart failure medication if GPs are not confident with HF medication titration or if they have any questions with HF care. NP helpline can be accessed during the study period, Monday to Friday, from 8 am to 4 pm) d) the mode of delivery: face-to-face of heart failure education; via telephone or video conference to support medication titration e) the number of times the intervention will be delivered and over what period of time: HF education 1 session *1 hour; GP/NP interactions will be ad hoc (as needed). f) the location/setting where the intervention occurs: FSH g) any strategies used to assess or monitor adherence or fidelity to the intervention: audit and feedback from patients/GPs

Sponsors

Curtin University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Men and women over the age of 18 years with a diagnosis of heart failure with reduced ejection fraction, with left ventricular ejection fraction less than 50%, life expectancy expected more than 6 months, able to identify provide contact details of a primary care general practitioner, willing to provide written informed consent.

Exclusion criteria

Patients attending the Advanced Heart Failure Service (FSH), patients who need palliative care, nursing homes/assisted living residents; impaired cognitive function; patients with end-stage renal failure (eGFR <15ml./min per 1.73 m2)

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 9, 2026