None listed
Conditions
Brief summary
The study investigates whether there is any additional benefit of adding atropine 0.025% insertion fluid when using Orthokeratology lenses to slow the progression of myopia (short-sight) in children.
Interventions
Use of atropine (0.025%) as the lubricant fluid used when inserting overnight orthokeratology contact lenses onto the cornea of the (experimental) eye. (The fluid normally used is saline) Dose: one drop, once daily, for two years, when inserting lenses at night. Administered by parent for younger children and by participant for older children: monitored by parental diary in both cases. Cross-over between eyes at one year with no washout period (for example: right eye receives atropine for one year followed by saline for one year, whereas left eye receives saline for one year followed by atropine for one year)
Sponsors
Study design
Eligibility
Inclusion criteria
Between 8 to 18 years of age Have successfully worn Orthokeratology for more than 3 months. Have a spectacle prescription of -0.75D to -6.00D spherical equivalent
Exclusion criteria
A difference in prescription between the two eyes greater than 1.50 Diopters Amblyopia, cataract or strabismus On medication that may interact with atropine A known allergy to anticholinergic drugs